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In this study, stress distributions in the <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> were analysed during prolonged clenching, using three\u2010dimensional finite element (<jats:styled-content style=\"fixed-case\">FE<\/jats:styled-content>) models of the <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> with and without disc displacement. The aim of this study was to investigate stress distribution of the cartilaginous tissues in the <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> with and without disc displacement. Finite element models were developed on the basis of magnetic resonance images from two subjects with and without anterior disc displacement. Condylar movements recorded during a 5\u2010min clenching were used as the loading condition for stress analysis. In the asymptomatic model, the highest von Mises stresses were located in the lateral area (4\u00b791\u00a0MPa) of the disc surfaces, and after 5\u2010min clenching, the higher stresses were still located at the lateral area (3\u00b765\u00a0MPa). In all the cartilaginous tissues, 30\u201350% of stress reduction occurred during 5\u2010min clenching. In contrast, the von Mises stress in the cartilaginous tissues of the symptomatic model with disc displacement was markedly lower, compared with the asymptomatic model. However, in the condylar cartilage, stress relaxation during clenching was not recognised. Furthermore, relatively high stresses were observed in the retrodiscal tissues throughout clenching. The present results indicate that disc position could be involved in the stress distribution of the <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> components during prolonged clenching.<\/jats:p>","DOI":"10.1111\/joor.12036","type":"journal-article","created":{"date-parts":[[2013,2,8]],"date-time":"2013-02-08T13:14:15Z","timestamp":1360329255000},"page":"239-246","source":"Crossref","is-referenced-by-count":38,"title":["Stress analysis in human temporomandibular joint affected by anterior disc displacement during prolonged clenching"],"prefix":"10.1111","volume":"40","author":[{"given":"S.","family":"Abe","sequence":"first","affiliation":[{"name":"Department of Oral Care and Clinical Education The Tokushima University Hospital Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Oral Care and Clinical Education The Tokushima University Hospital Tokushima Japan"},{"name":"Department of Comprehensive Dentistry Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Kohge","sequence":"additional","affiliation":[{"name":"Digital Solution Inc. 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