{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:14:33Z","timestamp":1787015673751,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T00:00:00Z","timestamp":1441324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["#2009\/15119\u20108"],"award-info":[{"award-number":["#2009\/15119\u20108"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["#2009\/17182\u20109"],"award-info":[{"award-number":["#2009\/17182\u20109"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Many chronic pain patients are refractory to treatment, which leads to the suspicion that somehow they are not fully effective and probably some mechanism of pain generation and\/or maintenance is still unknown. The aim of this cross\u2010sectional study was to provide evidence\u2010based data on pain mechanisms in different types of chronic pain conditions. Eighty women, with 18\u201365\u00a0years old, were included, divided into four groups: myofascial pain of the masticatory muscles (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a020), fibromyalgia (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a020), chronic daily headache and healthy volunteers (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a020). All patients were submitted to quantitative sensory tests: pressure pain threshold, mechanical detection threshold, mechanical pain threshold, ischaemic pain tolerance, cold pain sensitivity, aftersensation, wind\u2010up ratio and conditioned pain modulation. Current perception threshold was also determined (Neurometer\n                    <jats:styled-content style=\"fixed-case\">CPT<\/jats:styled-content>\n                    \/C \u2013 Neurotron\n                    <jats:sup>\u00ae<\/jats:sup>\n                    ). Three different zones were evaluated: trigeminal (masseter muscle), cervical and extratrigeminal (thenar eminence). Data were recorded and subjected to statistical analysis (\n                    <jats:sc>anova<\/jats:sc>\n                    , Tukey and Student's\n                    <jats:italic>t<\/jats:italic>\n                    \u2010tests). Masticatory myofascial pain, fibromyalgia and chronic daily headache individuals presented lower pressure pain thresholds than healthy volunteers (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00\u00b700). Chronic daily headache individuals had a significantly higher mechanical detection threshold than healthy volunteers (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00\u00b701). Individuals of the symptomatic groups showed lower values for mechanical pain threshold and for ischaemic pain tolerance (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00\u00b700) than healthy volunteers. The ability to activate the mechanism of endogenous modulation is impaired in women with fibromyalgia and myofascial pain (\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00\u00b700). These results reinforce evidence of central sensitisation and impaired endogenous modulation system in individuals with myofascial pain, fibromyalgia and chronic daily headache.\n                  <\/jats:p>","DOI":"10.1111\/joor.12344","type":"journal-article","created":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T05:46:29Z","timestamp":1441345589000},"page":"89-95","source":"Crossref","is-referenced-by-count":46,"title":["Somatosensory evaluation in Dysfunctional Syndrome patients"],"prefix":"10.1111","volume":"43","author":[{"given":"P. B.","family":"Hilgenberg\u2010Sydney","sequence":"first","affiliation":[{"name":"Dentistry Department Tuiuti University of Paran\u00e1 Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. A.","family":"Kowacs","sequence":"additional","affiliation":[{"name":"Neurological Institute of Curitiba (INC) Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. C. R.","family":"Conti","sequence":"additional","affiliation":[{"name":"Bauru School of Dentistry University of S\u00e3o Paulo Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,9,4]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Orofacial Pain: Guidelines for Assessment, Diagnosis, and Management","author":"De Leeuw R","year":"2008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780330203"},{"issue":"1","key":"e_1_2_7_4_1","first-page":"9","article-title":"The International Classification of Headache Disorders: 2nd ed","volume":"24","author":"Headache Classification Subcommittee of the International Headache Society","year":"2004","journal-title":"Cephalalgia"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2006.10.005"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2010.09.030"},{"key":"e_1_2_7_7_1","first-page":"318","article-title":"Pressure pain threshold in the detection of masticatory myofascial pain: an algometer\u2010based study","volume":"19","author":"Santos Silva RS","year":"2005","journal-title":"J Orofac Pain"},{"key":"e_1_2_7_8_1","first-page":"139","article-title":"Tactile and pain thresholds in patients with myofascial pain of the jaw muscles: a case\u2013control study","volume":"22","author":"Michelotti A","year":"2008","journal-title":"J Orofac Pain"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(02)00297-X"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(00)00432-2"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-3801(03)00082-X"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2006.01130.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(01)00396-7"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/08869634.1999.11746100"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.06.029"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2010.02196.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2006.01.041"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2005.02.003"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2004.03.004"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2010.10.008"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2010.04.009"},{"key":"e_1_2_7_22_1","first-page":"339","article-title":"Quantitative sensory testing in trigeminal nerve damage assessment","volume":"18","author":"Eliav E","year":"2004","journal-title":"J\u00a0Orofac Pain"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2010.107"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e32833c348b"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572003000100002"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI45178"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoor.12344","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoor.12344","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12344","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T08:18:49Z","timestamp":1696234729000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.12344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,4]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/joor.12344"],"URL":"https:\/\/doi.org\/10.1111\/joor.12344","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,4]]}}}