{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T03:36:43Z","timestamp":1771472203648,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Obstructive sleep apnoea\u2010hypopnea (<jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content>) is a common disorder characterised by repetitive complete or partial closure of the upper airway during sleep, which results in sleep fragmentation and oxygen desaturation. There is growing interest in the use of oral appliances (<jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content>s) to treat <jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content>. The purpose of this study was to clarify the cephalometric factors that are associated with <jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content> severity and that predict the outcome of <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content> therapy. Two hundred nine patients with <jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content> were recruited and analysed retrospectively. They had a polysomnographically documented apnoea\u2010hypopnea index (<jats:styled-content style=\"fixed-case\">AHI<\/jats:styled-content>) of more than five respiratory events per hour. Lateral skull radiographs were used for cephalometric analysis. Only 67 of the 209 recruited patients underwent a second polysomnography (<jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content>) to evaluate the efficacy of <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content> therapy. In all recruited patients, the angle formed by the subspinal point (A) to the nasion (N) to the supramental point (B) (i.e. <jats:styled-content style=\"fixed-case\">ANB<\/jats:styled-content> angle) and the distance between the mandibular plane and hyoid bone (<jats:styled-content style=\"fixed-case\">MP<\/jats:styled-content>\u2010H) were predictive factors of <jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content> severity. In only 67 patients underwent <jats:styled-content style=\"fixed-case\">PSG<\/jats:styled-content> with an <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content>, the mean rate of decrease in the <jats:styled-content style=\"fixed-case\">AHI<\/jats:styled-content> was 47\u00b78 \u00b1 29\u00b71%. <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content> therapy effectively treated <jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content> in some patients with a very severe form of <jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content>. However, patients who had a high position of the hyoid bone had a poor response to <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content> therapy. This study suggested that cephalometric analysis is useful for predicting <jats:styled-content style=\"fixed-case\">OSAH<\/jats:styled-content> severity and <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content> therapy efficacy.<\/jats:p>","DOI":"10.1111\/joor.12408","type":"journal-article","created":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T20:29:38Z","timestamp":1462134578000},"page":"649-655","source":"Crossref","is-referenced-by-count":12,"title":["Predictors of obstructive sleep apnoea\u2010hypopnea severity and oral appliance therapy efficacy by using lateral cephalometric analysis"],"prefix":"10.1111","volume":"43","author":[{"given":"Y.","family":"Sakamoto","sequence":"first","affiliation":[{"name":"Department of Clinical Oral Oncology Unit of Translational Medicine Graduate School of Biomedical Sciences Nagasaki University Nagasaki 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