{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T18:00:07Z","timestamp":1792864807345,"version":"4.5.0"},"reference-count":44,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T00:00:00Z","timestamp":1497830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010078","name":"Central Denmark Region","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010078","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The aim of this study is to investigate effects of transcranial direct current stimulation (<jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content>) on neuroplasticity in corticomotor pathways related to tongue muscles evoked by a training task using the tongue drive system (<jats:styled-content style=\"fixed-case\">TDS<\/jats:styled-content>). Using a crossover design, 13 healthy participants completed two sessions of <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content> while performing 30 min of <jats:styled-content style=\"fixed-case\">TDS<\/jats:styled-content> training. Sessions were spaced at least 2 weeks apart and participants randomly received anodal and sham <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content> stimulation in the first session and the other condition in the second session. Single and paired pulse transcranial magnetic stimulation was used to elicit motor evoked potentials (<jats:styled-content style=\"fixed-case\">MEP<\/jats:styled-content>s) of the tongue at three time\u2010points: before, immediately after and 30 min after training. Participant\u2010based reports of fun, pain, fatigue and motivation, level of difficulty and effort were evaluated on numerical rating scales. There was no consistent significant effect of anodal and sham stimulation on single or paired pulse stimulation <jats:styled-content style=\"fixed-case\">MEP<\/jats:styled-content> amplitude immediately or 30 min after <jats:styled-content style=\"fixed-case\">TDS<\/jats:styled-content> training. Irrespective of <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content> type, training with <jats:styled-content style=\"fixed-case\">TDS<\/jats:styled-content> induced cortical plasticity in terms of increased <jats:styled-content style=\"fixed-case\">MEP<\/jats:styled-content> amplitudes for higher stimulus intensities after 30 min compared with before and immediately after training. Participant\u2010based reports revealed no significant difference between <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content> conditions for level of fun, fatigue, motivation, difficulty and level of effort but a significant increase in pain in the anodal condition, although pain level was low for both conditions. In conclusion, tongue <jats:styled-content style=\"fixed-case\">MEP<\/jats:styled-content> amplitudes appear to be sensitive to training with the tongue using <jats:styled-content style=\"fixed-case\">TDS<\/jats:styled-content>; however, anodal <jats:styled-content style=\"fixed-case\">tDCS<\/jats:styled-content> does not have an impact on training\u2010evoked neuroplasticity of tongue corticomotor pathways.<\/jats:p>","DOI":"10.1111\/joor.12529","type":"journal-article","created":{"date-parts":[[2017,5,28]],"date-time":"2017-05-28T13:16:38Z","timestamp":1495977398000},"page":"691-701","source":"Crossref","is-referenced-by-count":9,"title":["Effect of transcranial direct current stimulation on neuroplasticity in corticomotor pathways of the tongue muscles"],"prefix":"10.1111","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8191-9769","authenticated-orcid":false,"given":"M.","family":"Kothari","sequence":"first","affiliation":[{"name":"Hammel Neurorehabilitation Centre and University Research Clinic Aarhus University Hammel Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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