{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:29:42Z","timestamp":1787581782633,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,12,7]],"date-time":"2017-12-07T00:00:00Z","timestamp":1512604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R01 2DE016417"],"award-info":[{"award-number":["R01 2DE016417"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Energy densities (<jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> mJ<\/jats:styled-content>\/mm<jats:sup>3<\/jats:sup>) quantify mechanical work imposed on articular cartilages during function. This cross\u2010sectional study examined differences in temporomandibular joint (<jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> during asymmetric versus symmetric jaw closing in healthy females versus males. <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> component variables were tested for differences between and within sexes for two types of jaw closing. Seventeen female and 17 male subjects gave informed consent to participate. Diagnostic criteria for temporomandibular disorders and images (magnetic resonance (<jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>), computed tomography) were used to confirm healthy <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> status. Numerical modelling predicted <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> loads (<jats:italic>F<\/jats:italic><jats:sub>normal<\/jats:sub>) consequent to unilateral canine biting. Dynamic stereometry combined <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> imaging and jaw\u2010tracking data to measure <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> component variables during 10 trials of each type of jaw closing in each subject's <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content>s. These data were then used to calculate <jats:styled-content style=\"fixed-case\">TMJ ED<\/jats:styled-content> during jaw closing asymmetrically and symmetrically. Paired and Student's t tests assessed <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> between jaw closing movements and sexes, respectively. Multivariate data analyses assessed <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> component variable differences between jaw closing movements and sexes (\u03b1\u00a0=\u00a00.05). Contralateral <jats:styled-content style=\"fixed-case\">TMJ ED<\/jats:styled-content> were 3.6\u2010fold and significantly larger (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001) during asymmetric versus symmetric jaw closing, due to significantly larger (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a0.001) distances of <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> stress\u2010field translation in asymmetric versus symmetric movement. During asymmetric jaw closing, contralateral <jats:styled-content style=\"fixed-case\">TMJ ED<\/jats:styled-content> were twofold and significantly larger (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.036) in females versus males, due to 1.5\u2010fold and significantly smaller (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a0.010) <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> disc cartilage volumes under stress fields in females versus males. These results suggest that in healthy individuals, asymmetric compared to symmetric jaw closure in females compared to males has higher <jats:styled-content style=\"fixed-case\">TMJ<\/jats:styled-content> mechanical fatigue liabilities.<\/jats:p>","DOI":"10.1111\/joor.12588","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T04:02:46Z","timestamp":1511323366000},"page":"97-103","source":"Crossref","is-referenced-by-count":10,"title":["Jaw closing movement and sex differences in temporomandibular joint energy densities"],"prefix":"10.1111","volume":"45","author":[{"given":"L. M.","family":"Gallo","sequence":"first","affiliation":[{"name":"Department of Masticatory Disorders School of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Fankhauser","sequence":"additional","affiliation":[{"name":"Department of Masticatory Disorders School of Dental Medicine University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. M.","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostic Sciences School of Dental Medicine University at Buffalo  Buffalo NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Liu","sequence":"additional","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics and Oral &amp; Craniofacial Sciences School of Dentistry University of Missouri\u2010Kansas City  Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics &amp; Epidemiology East Tennessee State University  Johnson City TN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Nickel","sequence":"additional","affiliation":[{"name":"Departments of Orthodontics &amp; Dentofacial Orthopedics and Oral &amp; Craniofacial Sciences School of Dentistry University of Missouri\u2010Kansas City  Kansas City MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3834-7918","authenticated-orcid":false,"given":"L. 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