{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T20:33:42Z","timestamp":1776803622860,"version":"3.51.2"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T00:00:00Z","timestamp":1513814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007951","name":"Tokyo Medical and Dental University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007951","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP17H00755"],"award-info":[{"award-number":["JP17H00755"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["15K20508"],"award-info":[{"award-number":["15K20508"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["15KK0336"],"award-info":[{"award-number":["15KK0336"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Among the functional disabilities that patients face following maxillectomy, speech impairment is a major factor influencing quality of life. Proper rehabilitation of speech, which may include prosthodontic and surgical treatments and speech therapy, requires accurate evaluation of speech intelligibility (<jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content>). A simple, less time\u2010consuming yet accurate evaluation is desirable both for maxillectomy patients and the various clinicians providing maxillofacial treatment. This study sought to determine the utility of digital acoustic analysis of vowels for the prediction of <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> in maxillectomy patients, based on a comprehensive understanding of speech production in the vocal tract of maxillectomy patients and its perception. Speech samples were collected from 33 male maxillectomy patients (mean age 57.4\u00a0years) in two conditions, without and with a maxillofacial prosthesis, and formant data for the vowels \/a\/,\/e\/,\/i\/,\/o\/, and \/u\/ were calculated based on linear predictive coding. The frequency range of formant 2 (F2) was determined by differences between the minimum and maximum frequency. An <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> test was also conducted to reveal the relationship between <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> score and F2 range. Statistical analyses were applied. F2 range and <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> score were significantly different between the two conditions without and with a prosthesis (both <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001). F2 range was significantly correlated with <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> score in both the conditions (Spearman's <jats:italic>r<\/jats:italic>\u00a0=\u00a0.843, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001; <jats:italic>r<\/jats:italic>\u00a0=\u00a0.832, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001, respectively). These findings indicate that calculating the F2 range from 5 vowels has clinical utility for the prediction of <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> after maxillectomy.<\/jats:p>","DOI":"10.1111\/joor.12595","type":"journal-article","created":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T11:33:02Z","timestamp":1512473582000},"page":"216-221","source":"Crossref","is-referenced-by-count":13,"title":["Digitised evaluation of speech intelligibility using vowels in maxillectomy patients"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3982-8369","authenticated-orcid":false,"given":"Y. I.","family":"Sumita","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Prosthetics Graduate School Tokyo Medical and Dental University (TMDU)  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hattori","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Prosthetics Graduate School Tokyo Medical and Dental University (TMDU)  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Murase","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Prosthetics Graduate School Tokyo Medical and Dental University (TMDU)  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. E.","family":"Elbashti","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Prosthetics Graduate School Tokyo Medical and Dental University (TMDU)  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Taniguchi","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Prosthetics Graduate School Tokyo Medical and Dental University (TMDU)  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjom.2001.0706"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2013.02.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2012.00662.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2186\/ajps.5.56"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"925707","DOI":"10.1155\/2014\/925707","article-title":"Measurement of voice onset time in maxillectomy patients","volume":"2014","author":"Hattori M","year":"2014","journal-title":"ScientificWorldJournal"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2842.1998.00238.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpor.2010.04.007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpor.2009.07.004"},{"key":"e_1_2_7_10_1","first-page":"507","article-title":"Three monosyllables for standard words in nasometer test: to evaluate air leakage in maxillectomy patients","volume":"52","author":"Prunkngarmpun C","year":"2008","journal-title":"J Prosthodont Res"},{"key":"e_1_2_7_11_1","first-page":"1","article-title":"Evaluation of voice production by acoustic measurements in mandibulectomy patients","volume":"31","author":"Murase M","year":"2008","journal-title":"Maxillofacial Prosthetics"},{"key":"e_1_2_7_12_1","volume-title":"The Vowel, Its Nature and Structure","author":"Chiba T","year":"1942"},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1250\/ast.37.148","article-title":"Vocal\u2010tract models and their applications in education for intuitive understanding of speech production","volume":"37","author":"Arai T","year":"2016","journal-title":"Acoust Sci & Tech"},{"key":"e_1_2_7_14_1","first-page":"31","article-title":"The replication of Chiba and Kajiyama's mechanical models of the human vocal cavity","volume":"5","author":"Arai T","year":"2001","journal-title":"J Phonetic Soc Japan"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshr.3805.1001"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1044\/jshr.3003.301"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2014.10.002"},{"key":"e_1_2_7_18_1","volume-title":"Acoustic Theory of Speech Production","author":"Fant G","year":"1970"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvoice.2008.10.013"},{"key":"e_1_2_7_20_1","first-page":"137","volume-title":"Computed Tomography \u2010 Clinical Applications","author":"Inohara K","year":"2012"},{"key":"e_1_2_7_21_1","first-page":"63","volume-title":"Selected Topics on Computed Tomography","author":"Sumita Y","year":"2013"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2842.2002.00911.x"},{"key":"e_1_2_7_23_1","first-page":"1","article-title":"Digitized speech characteristics in patients with maxillectomy defects","author":"Elbashti ME","year":"2017","journal-title":"J Prosthodont"},{"key":"e_1_2_7_24_1","first-page":"25","article-title":"A speech synthesis device for voice disorders: its research approach and design concept","volume":"106","author":"Yabu K","year":"2007","journal-title":"IEICE Technical Report"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.1908024"},{"key":"e_1_2_7_26_1","unstructured":"HashibaM YabuK TakaseM SugaiY IfukubeT.Development of a real\u2010time speech synthesis application software for smartphone controlled by finger positions and movements. 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