{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:32:07Z","timestamp":1774261927306,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,13]],"date-time":"2018-01-13T00:00:00Z","timestamp":1515801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17K11767"],"award-info":[{"award-number":["17K11767"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2018,3]]},"abstract":"Summary<\/jats:title>There is little evidence of sensation in individuals with diabetes mellitus (DM<\/jats:styled-content>) in the dental research field. We investigated whether pain thresholds (PT<\/jats:styled-content>s) differ between individuals with and without DM<\/jats:styled-content> (non\u2010DM<\/jats:styled-content>; NDM<\/jats:styled-content>). To this end, we assessed whether PT<\/jats:styled-content>s obtained from the oral cavity, hands, and feet differed from each other and across groups, and whether PT<\/jats:styled-content>s differed for the three current frequencies used for testing (2000\u00a0Hz, 250\u00a0Hz, and 5\u00a0Hz). Pain threshold measurements were obtained from the oral mucosa and the tips of the fingers and toes of 56 volunteers, including 21 individuals with DM<\/jats:styled-content> (12 men and 9 women, average age: 72.1\u00a0\u00b1\u00a04.7\u00a0years) and 35 NDM<\/jats:styled-content> individuals (17 males and 18 females, average age: 51.2\u00a0\u00b1\u00a023.9\u00a0years) using the Neurometer CPT<\/jats:styled-content>\/C\u00ae<\/jats:sup> device to deliver electrical stimulation. A single operator obtained PT<\/jats:styled-content> measurements from around the left greater palatine foramen and from the tip of the left first finger and of the left great toe. Individuals with DM<\/jats:styled-content> had significantly lower PT<\/jats:styled-content> values than those without DM<\/jats:styled-content>. The PT<\/jats:styled-content> values for the oral cavity, hands, and feet differed significantly from each other (foot\u00a0>\u00a0hand, foot\u00a0>\u00a0oral cavity, hand\u00a0>\u00a0oral cavity). Moreover, there was a significant difference in the PT<\/jats:styled-content> values for 5\u00a0Hz and 2000\u00a0Hz, as well as for 250\u00a0Hz and 2000\u00a0Hz. This study concluded that PT<\/jats:styled-content> values derived from DM<\/jats:styled-content> participants are lower than those from NDM<\/jats:styled-content> participants, although PT<\/jats:styled-content> measurements varied across regions and with current frequency.<\/jats:p>","DOI":"10.1111\/joor.12601","type":"journal-article","created":{"date-parts":[[2017,12,28]],"date-time":"2017-12-28T23:02:38Z","timestamp":1514502158000},"page":"235-239","source":"Crossref","is-referenced-by-count":8,"title":["Differences in pain thresholds elicited by intraoral electrical stimuli between individuals with and without diabetes mellitus"],"prefix":"10.1111","volume":"45","author":[{"given":"T.","family":"Ogawa","sequence":"first","affiliation":[{"name":"Removable Prosthodontics Nihon University Graduate School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kimoto","sequence":"additional","affiliation":[{"name":"Department of Removable Prosthodontics Nihon University School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Removable Prosthodontics Nihon University School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Furuse","sequence":"additional","affiliation":[{"name":"Removable Prosthodontics Nihon University Graduate School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ono","sequence":"additional","affiliation":[{"name":"Removable Prosthodontics Nihon University Graduate School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Furokawa","sequence":"additional","affiliation":[{"name":"Removable Prosthodontics Nihon University Graduate School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Okubo","sequence":"additional","affiliation":[{"name":"Department of Removable Prosthodontics Nihon University School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Nihon University School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Kawai","sequence":"additional","affiliation":[{"name":"Department of Removable Prosthodontics Nihon University School of Dentistry at Matsudo Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,13]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Global Report on Diabetes","author":"World Health Organization","year":"2016"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2017.03.011"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.12650"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.07.048"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2000.107536"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/23328940.2015.1131506"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.05.017"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/193229681300700510"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-35552012005000083"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2011.03308.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8227(95)01107-O"},{"key":"e_1_2_7_13_1","first-page":"210","article-title":"Constant current sine wave transcutaneous nerve stimulation for the evaluation of peripheral neuropathy","volume":"68","author":"Katims JJ","year":"1987","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.1991.tb02159.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.1994.tb00371.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.14"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ger.12006"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpor.2012.09.001"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.75"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.23.4.510"},{"key":"e_1_2_7_21_1","first-page":"711","article-title":"Current perception threshold in evaluating diabetic neuropathy","volume":"40","author":"Umezawa S","year":"1997","journal-title":"J Japan Diab Soc"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199911)22:11<1531::AID-MUS7>3.0.CO;2-O"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.10.1sup_33"},{"key":"e_1_2_7_24_1","first-page":"286","article-title":"Reliability and characteristics of current perception thresholds in the territory of the infraorbital and inferior alveolar nerves","volume":"14","author":"Kim HS","year":"2000","journal-title":"J Orofac Pain"},{"key":"e_1_2_7_25_1","first-page":"423","article-title":"Perception thresholds for electrical stimulation of the palatal mucosa","volume":"20","author":"Ogura K","year":"2007","journal-title":"Int J Prosthodont"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(20000228)418:1<1::AID-CNE1>3.0.CO;2-P"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1979.sp012619"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)90932-0"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.52.4.502"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199501000-00009"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/ner.12249"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoor.12601","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T17:41:21Z","timestamp":1695750081000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.12601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,13]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/joor.12601"],"URL":"https:\/\/doi.org\/10.1111\/joor.12601","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,13]]}}}