{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T01:34:13Z","timestamp":1791855253710,"version":"4.3.4"},"reference-count":93,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,5,9]],"date-time":"2018-05-09T00:00:00Z","timestamp":1525824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>Hypohidrotic ectodermal dysplasia (<jats:styled-content style=\"fixed-case\">HED<\/jats:styled-content>) comprises a large group of inherited disorders of ectodermal structures, characterised by hypo\u2010 or anhidrosis, hypotrichosis and hypo\u2010 or oligo\u2010 or anodontia. We aimed to systematically assess the spectrum of prosthodontic approaches with regard to the patients' age and to provide clinical implications for practicing dentists. An electronic and manual search was conducted in four databases (Medline, <jats:styled-content style=\"fixed-case\">LIVIVO<\/jats:styled-content>, Cochrane Library, Web of Science Core Collection). Publications of multiple study designs written in English or German without data restrictions, reporting on prosthodontic treatment of patients diagnosed with <jats:styled-content style=\"fixed-case\">HED<\/jats:styled-content> and afflicted with oligo\u2010 or anodontia, were included. In total, 75 articles on 146 patients were analysed according to the patients\u2032 age. In children aged 2\u201017\u00a0years, removable full or partial (over)dentures represented standard treatment. In the mandible, implant\u2010supported removable dentures on two interforaminal implants presented an alternative, already in young childhood. In cases with more than six teeth per jaw, also fixed (resin) bridges were used, frequently after orthodontic treatment. In adults, fixed or removable reconstructions with the help of up to eight implants per jaw, usually placed after bone augmentation procedures, were standard. Ten case reports\/series with long\u2010term follow\u2010up illustrated the need for consistent maintenance including denture renewals. Prosthodontic rehabilitation should start in early childhood and needs to be revised in accordance with the patients' growth. Treatment should be carried out by a multidisciplinary team addressing variable demands in different age groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.12638","type":"journal-article","created":{"date-parts":[[2018,4,21]],"date-time":"2018-04-21T12:38:54Z","timestamp":1524314334000},"page":"555-570","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: A systematic review"],"prefix":"10.1111","volume":"45","author":[{"given":"D.","family":"Schnabl","sequence":"first","affiliation":[{"name":"University Hospital for Dental Prosthetics and Restorative Dentistry Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Grunert","sequence":"additional","affiliation":[{"name":"University Hospital for Dental Prosthetics and Restorative Dentistry Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Schmuth","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6169-6812","authenticated-orcid":false,"given":"I.","family":"Kapferer\u2010Seebacher","sequence":"additional","affiliation":[{"name":"University Hospital for Dental Prosthetics and Restorative Dentistry Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,9]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Dento\/Oro\/Craniofacial Anomalies abd Genetics","author":"Bloch\u2010Zupan A","year":"2012"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2013.09.004"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21384"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2014.01.004"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2006.01628.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2980"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2981"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/ejo\/18.1.119","article-title":"A multidisciplinary approach to oral rehabilitation with osseointegrated implants in children and adolescents with multiple aplasia","volume":"18","author":"Bergendal B","year":"1996","journal-title":"Eur J Orthod"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2535"},{"key":"e_1_2_7_11_1","unstructured":"National Heart BaLI.Quality assessment tools.https:\/\/www.nhlbi.nih.gov\/health-pro\/guidelines\/in-develop\/cardiovascular-risk-reduction\/tools. 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