{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T11:26:39Z","timestamp":1788953199132,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T00:00:00Z","timestamp":1530144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>Curcumin is a turmeric\u2010contained active ingredient that has been proven to be effective in treating pain and inflammation due to its analgesic as well as anti\u2010inflammation potential. Odontectomy, on the other hand, has been well known for its post\u2010procedure acute inflammation pain. The aim of the current study was to evaluate the efficacy of curcuminoid in treating acute inflammation post\u2010operative pain in the post\u2010surgical removal of impacted third molars patients. Ninety (44 males; 46 females) participants were recruited in this randomised controlled trial and randomly assigned to the control group (those who consumed mefenamic acid) or the experimental group (those who consumed curcumin).<jats:italic>Numeric rating scale<\/jats:italic>(<jats:styled-content style=\"fixed-case\">NRS<\/jats:styled-content>) was used as an evaluation tool to evaluate the intensity of the pain experienced by the participants. Pain evaluation was performed immediately after anaesthesia effect disappeared (T<jats:sub>0<\/jats:sub>) and an hour after participant took their first (T<jats:sub>1<\/jats:sub>), second (T<jats:sub>2<\/jats:sub>) and third (T<jats:sub>3<\/jats:sub>) course of drugs. All data were collected and analysed using Wilcoxon\u2010Mann\u2010Whitney test. The current study showed that participants in both groups experienced significantly (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.01) less pain compared to their initial pain level. In addition, when the two groups were compared, it was revealed that those in the treatment group experienced even significantly (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.01) less pain compared to those in the control group. It can be concluded that curcumin is effective in treating acute inflammation pain in the post\u2010surgical removal of impacted third molars patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.12679","type":"journal-article","created":{"date-parts":[[2018,6,16]],"date-time":"2018-06-16T09:54:37Z","timestamp":1529142877000},"page":"677-683","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["The efficacy of curcumin in managing acute inflammation pain on the post\u2010surgical removal of impacted third molars patients: A randomised controlled trial"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6975-990X","authenticated-orcid":false,"given":"T.","family":"Maulina","sequence":"first","affiliation":[{"name":"Faculty of Dentistry Oral Surgery Department Universitas Padjadjaran Bandung 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