{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T20:00:18Z","timestamp":1781121618152,"version":"3.54.1"},"reference-count":37,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T00:00:00Z","timestamp":1536883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25750236"],"award-info":[{"award-number":["25750236"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To assess the effect of age on swallowing with a focus on structural movement, timing and duration of physiologic events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary University Medical Center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Community\u2010dwelling adults (3 age groups): younger 20 to 39 (n\u00a0=\u00a023; mean 32\u00a0\u00b1\u00a05), middle\u2010aged 40 to 59 (n\u00a0=\u00a029; mean 49\u00a0\u00b1\u00a05) and older adults 60 to 74 (n\u00a0=\u00a015; mean 67\u00a0\u00b1\u00a05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>One 10\u2010<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content> honey\u2010thick liquid (1700 <jats:styled-content style=\"fixed-case\">mP<\/jats:styled-content>a) swallow was studied using 320\u2010row area detector computed tomography scanning.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p>Kinematic analysis was performed for each swallow including temporal characteristics and structural movements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The duration of velopharyngeal closure and laryngeal closure (including epiglottis inversion, laryngeal vestibule closure, true vocal cord closure) was significantly different by age group (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.002, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.017, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.041, respectively). Events were prolonged in older adults compared with middle\u2010aged and younger adults. The pharyngeal phase was longer for older adults. Velopharyngeal closure started earlier and continued until after complete <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> opening. In younger adults, velopharyngeal and laryngeal opening occurred before complete <jats:styled-content style=\"fixed-case\">UES<\/jats:styled-content> opening. No differences were found in bolus movement through the oropharynx by group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>During swallowing, older adults had a longer pharyngeal phase characterised by prolonged velopharyngeal and laryngeal closure. This difference may be a protective mechanism to compensate for age\u2010related weakness. A better understanding of the mechanism by which this adaptation occurs is needed to tailor rehabilitation strategies and to maintain swallowing function during the lifespan.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.12703","type":"journal-article","created":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T15:09:04Z","timestamp":1534950544000},"page":"959-966","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Pharyngeal swallowing in older adults: Kinematic analysis using three\u2010dimensional dynamic computed tomography"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8536-5487","authenticated-orcid":false,"given":"Kannit","family":"Pongpipatpaiboon","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine I School of Medicine Fujita Health University  Toyoake 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