{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T15:32:17Z","timestamp":1789399937855,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005934","name":"Malm\u00f6 H\u00f6gskola","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005934","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the outcomes of two emergency treatment procedures to alleviate pain from localised symptomatic apical periodontitis: complete chemo\u2010mechanical disinfection (<jats:styled-content style=\"fixed-case\">CMD<\/jats:styled-content>) of the root canal system, or removal of necrotic tissue from the pulp chamber (<jats:styled-content style=\"fixed-case\">RNT<\/jats:styled-content>), <jats:italic>that is<\/jats:italic> without instrumentation of the root canals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010seven consecutive patients from the emergency clinic at Malm\u00f6 University met the inclusion criteria: spontaneous pain and\/or pain on percussion and palpation, non\u2010bleeding pulp in the canal orifice, pain \u22654 on a Numeric Rating Scale and \u226518\u00a0years of age. The diagnosis was symptomatic apical periodontitis, in the absence of swelling and\/or fever. Pre\u2010operative pain levels and intake of analgesics were registered. The patients were randomised to one of the two treatment groups. Three to five days post\u2010operatively, the patients were contacted by telephone and asked to grade their current pain level and report any post\u2010operative intake of analgesics and antibiotics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the patients treated with <jats:styled-content style=\"fixed-case\">CMD<\/jats:styled-content> of the root canal system, 26\/30 (87%) reported satisfactory pain relief, compared with 22\/27 (81%) of those treated by <jats:styled-content style=\"fixed-case\">RNT<\/jats:styled-content>. There was no mean difference in pain relief between the two groups (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.879). Post\u2010operatively, 37% in each group reported using analgesics and one in each group reported using antibiotics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Three to five days after treatment, a majority (&gt;80%) in both groups reported adequate pain relief, in some cases in combination with analgesics. Removal of necrotic and infected tissue from the pulp chamber might therefore be a cost\u2010effective <jats:italic>emergency<\/jats:italic> treatment alternative to complete chemo\u2010mechanical disinfection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.12730","type":"journal-article","created":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T14:22:13Z","timestamp":1539267733000},"page":"120-126","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Alleviation of acute dental pain from localised apical periodontitis: A prospective randomised study comparing two emergency treatment procedures"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7425-1038","authenticated-orcid":false,"given":"Eva","family":"Wolf","sequence":"first","affiliation":[{"name":"Department of Endodontics Faculty of Odontology Malm\u00f6 University  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mille","family":"Dragicevic","sequence":"additional","affiliation":[{"name":"Department of Endodontics Faculty of Odontology Malm\u00f6 University  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e4rta","family":"Fuhrmann","sequence":"additional","affiliation":[{"name":"Department of Endodontics Faculty of Odontology Malm\u00f6 University  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2006.tb00472.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/030006059802600506"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(96)80054-0"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200102000-00016"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12741"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12781"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(89)80219-5"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(92)90330-S"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6831-6-1"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(84)90086-0"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01511.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/eje.12066"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199311000-00029"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.87802"},{"key":"e_1_2_7_16_1","first-page":"449","article-title":"The effects of surgical exposures of dental pulps in germfree and conventional laboratory rats","volume":"34","author":"Kakehashi S","year":"1966","journal-title":"J South Calif Dent Assoc"},{"key":"e_1_2_7_17_1","first-page":"1","article-title":"Microbiological examination of root canals and periapical tissues of human teeth. 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