{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T06:20:51Z","timestamp":1778221251374,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,2,5]],"date-time":"2019-02-05T00:00:00Z","timestamp":1549324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Oromandibular dystonia (OMD) with involuntary jaw and tongue movements may be misdiagnosed as temporomandibular disorders (TMD) and because of the complex muscle activity and involvement of several small muscles, OMD is also considered difficult to treat.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim was to evaluate OMD in patients 8\u201010\u00a0years after start of treatment with botulinum toxin (BoNT) by self\u2010reported and standardised global scales and questionnaires.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Of 21 previously reported patients with OMD, 14 responded to a mail health questionnaire to describe the disease course and treatment effect as well as the overall impact of OMD by a visual analogue scale (VAS), the Patient Health Questionnaire (PHQ) for depression and anxiety, and the Jaw Functional Limitation Scale (JFLS). The results were analysed with non\u2010parametric statistical analysis (Wilcoxon matched\u2010pairs test and Spearman's rank\u2010order correlations).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The OMD was still present in 13 patients. In nine patients, the BoNT treatment had continued as monotherapy or combined with oral medication. VAS for OMD was significantly reduced (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.04) over the years, and most patients felt improvement from the treatment. However, the patients had still some functional limitations, typically regarding jaw mobility and communication, and both JFLS and mental distress (PHQ) were significantly correlated with the OMD VAS (<jats:italic>r<\/jats:italic><jats:sub>S<\/jats:sub> 0.77 and 0.74).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results showed marked reduction of the experienced OMD with treatment and over time, and also stressed similarities between OMD and TMD. Both dentists and neurologists should be aware of this overlap and reduce misdiagnosis by applying an interdisciplinary approach.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.12768","type":"journal-article","created":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T17:54:55Z","timestamp":1548093295000},"page":"441-449","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Oromandibular dystonia, mental distress and oro\u2010facial dysfunction\u2014A follow\u2010up 8\u201010\u00a0years after start of treatment with botulinum toxin"],"prefix":"10.1111","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0398-6541","authenticated-orcid":false,"given":"Merete","family":"Bakke","sequence":"first","affiliation":[{"name":"Clinical Oral Physiology, Department of Odontology, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Baram","sequence":"additional","affiliation":[{"name":"Clinical Oral Physiology, Department of Odontology, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torben","family":"Dalager","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology and Dystonia Clinic, Department of Neurology Bispebjerg University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi Bryde","family":"Biernat","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology and Dystonia Clinic, Department of Neurology Bispebjerg University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eigild","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology and Dystonia Clinic, Department of Neurology Bispebjerg University Hospital Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25475"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-52014-2.00037-9"},{"key":"e_1_2_8_4_1","unstructured":"What is dystonia?https:\/\/www.dystonia-foundation.org\/what-is-dystonia\/forms-of-dystonia\/focal-dystonias\/more-on-oromandibular-dystonia. Accessed August 23 2018."},{"key":"e_1_2_8_5_1","first-page":"10","article-title":"Oral dyskinesia: a clinical overview","volume":"18","author":"Blanchet PJ","year":"2005","journal-title":"Int J Prosthodont"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21304"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.04.023"},{"key":"e_1_2_8_8_1","first-page":"236","volume-title":"Clinical Cases in Orofacial Pain","author":"Bakke M","year":"2017"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2003.00664.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2012.09.011"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.9.2102"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2007.12.010"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.14802\/jmd.17065"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2006.09.005"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1602836"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2015.09.001"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2012.12.004"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2017.09.003"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-018-0488-3"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2018.02.006"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.127.4.389"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/014556131109000210"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23265"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8185-1"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2016.06.028"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-018-0620-9"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25579"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.11607\/jop.1151"},{"key":"e_1_2_8_29_1","unstructured":"Diagnostic criteria for temporomandibular disorders (DC\/TMD) scoring manual for self\u2010report instruments prepared by Richard Ohrbach (University at Buffalo NY US) and Wendy Knibbe (ACTA Amsterdam The Netherlands) Version: January 9 2017.https:\/\/ubwp.buffalo.edu\/rdc-tmdinternational\/tmd-assessmentdiagnosis\/dc-tmd\/. Accessed August 23 2018."},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2015.09.010"},{"key":"e_1_2_8_31_1","first-page":"219","article-title":"The jaw functional limitation scale: development, reliability, and validity of 8\u2010item and 20\u2010item versions","volume":"22","author":"Ohrbach R","year":"2008","journal-title":"J Orofac Pain"},{"key":"e_1_2_8_32_1","unstructured":"DC-TMD-Self-report-Instrument-Scoring-Manual.https:\/\/pdfs.semanticscholar.org\/cd4d\/02d053397fd81cdbedd1d7def64f172280a7.pdf. Accessed August 23 2018."},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.50.6.613"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoor.12768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joor.12768","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T16:57:56Z","timestamp":1694365076000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.12768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,5]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/joor.12768"],"URL":"https:\/\/doi.org\/10.1111\/joor.12768","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,5]]},"assertion":[{"value":"2018-09-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}