{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:17:01Z","timestamp":1761581821779,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T00:00:00Z","timestamp":1557619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the predictive value of side effects on usage times during the initial titration phase of oral appliance therapy for sleep apnoea. The secondary objective was to assess the correlation between subjective and objective usage times.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 21 subjects diagnosed with sleep apnoea and a history of non\u2010compliance with CPAP therapy were enrolled in the 4\u2010week clinical study. Objective compliance was assessed through an intra\u2010oral compliance monitor embedded in a Thornton Adjustable Positioner. Subjective compliance was evaluated through self\u2010reporting and questionnaire for side effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Excess salivation, xerostomia and tooth discomfort were the most common side effects (61%\u201067%). Noises (OR\u00a0=\u00a010, 95% CI\u00a0=\u00a00.85\u2010117.02, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.067), jaw discomfort (OR\u00a0=\u00a015, 95% CI\u00a0=\u00a01.21\u2010185.20, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.035) and gum discomfort (OR\u00a0=\u00a08.86, 95% CI\u00a0=\u00a01.0\u2010\u221e, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.038) were highly predictive of non\u2010compliance. Subjects with either \u201cnone\u201d or \u201cmild\u201d side effects recorded a mean oral appliance usage time \u22655.5\u00a0hours\/night, while subjects reporting \u201csevere\u201d side effects recorded a mean usage time \u22644\u00a0hours\/night. The mean usage time was 5.49\u00a0hours\/night, with nightly compliance (defined as &gt;4\u00a0hours per night for 70% the nights per week) at 33%. Nonetheless, compliance increased from 26%\u201050% from week 1 to week 4. The subjective and objective usage times were highly correlated (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.81).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was a high correlation between subjective and objective compliance reporting data. Moderate\/severe side effects had the greatest effect on compliance.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.12802","type":"journal-article","created":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T07:46:08Z","timestamp":1555400768000},"page":"715-722","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Influence of short\u2010term side effects on oral sleep appliance compliance among CPAP\u2010intolerant patients: An objective monitoring of compliance"],"prefix":"10.1111","volume":"46","author":[{"given":"Shane","family":"Mullane","sequence":"first","affiliation":[{"name":"Private Practice, Prosthodontics Newcastle West, Co. Limerick Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1634-2932","authenticated-orcid":false,"given":"Weiqiang","family":"Loke","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Dentistry National University of Singapore Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B0-72-160797-7\/50098-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2008.02.003"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.6.9808095"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.156.6.9610026"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.14.1906"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.10.102"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.4858"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.8978"},{"issue":"1","key":"e_1_2_8_10_1","first-page":"CD004435","article-title":"Oral appliances for obstructive sleep apnoea","author":"Lim J","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-006-0084-8"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200701-114OC"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/154411130401500303"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.2.244"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.2.375"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/147.4.887"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-0613"},{"issue":"4","key":"e_1_2_8_18_1","first-page":"S172","article-title":"Treatment, airway and compliance effects of a titratable oral appliance","volume":"23","author":"Lowe AA","year":"2000","journal-title":"Sleep"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-8425.2009.00402.x"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jopr.12076"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3460"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2000.0275"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12802","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joor.12802","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12802","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T11:29:16Z","timestamp":1694258956000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.12802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,12]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1111\/joor.12802"],"URL":"https:\/\/doi.org\/10.1111\/joor.12802","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"type":"print","value":"0305-182X"},{"type":"electronic","value":"1365-2842"}],"subject":[],"published":{"date-parts":[[2019,5,12]]},"assertion":[{"value":"2018-08-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}