{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:21:08Z","timestamp":1761718868065,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,10,6]],"date-time":"2019-10-06T00:00:00Z","timestamp":1570320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Excessive daytime sleepiness (EDS) is frequently reported as a symptom for obstructive sleep apnoea (OSA), leading to problems with concentration, mood and memory. Mandibular advance device (MAD) is considered as an effective therapy to control OSA, reducing EDS and improving sleep quality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The present study aimed to investigate the effects MAD therapy on EDS of patients diagnosed with OSA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten patients from the Sleep Medicine Service of the \u201cHospital Geral Sanat\u00f3rio\u201d (Macei\u00f3, Alagoas, Brazil) were diagnosed with EDS, and a personalised MAD was made for each one of them. Nocturnal polysomnography (NPSG) and maintenance of wakefulness test (MWT) were applied before (baseline) and 3\u00a0months after the continuous use of the MAD. The number of arousals and micro\u2010arousals at baseline and after treatment was also evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 10 patients completed the investigation. A significant decrease in the number of arousals and micro\u2010arousals per night of sleep was observed after the use of MAD for three consecutive months (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.0078; Wilcoxon signed\u2010rank test). Also, there was a significant reduction on the apnoea\/hypopnea index between baseline and post\u2010treatment values (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.0001; paired <jats:italic>t<\/jats:italic> test), as well as an increase in the mean latency for the onset of sleep (MSL) in the MTW (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.0047; paired <jats:italic>t<\/jats:italic> test), indicating a significant difference among baseline and after treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We conclude that the improvement on EDS is associated with the used of MAD in patients diagnosed with OSA, improving their quality of sleep.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.12898","type":"journal-article","created":{"date-parts":[[2019,10,6]],"date-time":"2019-10-06T08:55:18Z","timestamp":1570352118000},"page":"1031-1035","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Association between mandibular advancement device therapy and reduction of excessive daytime sleepiness due to obstructive sleep apnoea"],"prefix":"10.1111","volume":"46","author":[{"given":"Cynthia Valeria","family":"Silva Gomes Ribeiro","sequence":"first","affiliation":[{"name":"Faculdade de Odontologia da UFAL Universidade Federal de Alagoas Maceio AL Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Djalma","family":"Ribeiro\u2010Sobrinho","sequence":"additional","affiliation":[{"name":"Faculdade de Odontologia da UFAL Universidade Federal de Alagoas Maceio AL Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1134-8542","authenticated-orcid":false,"given":"Victor Ricardo Manuel","family":"Mu\u00f1oz Lora","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Periodontology. Piracicaba Dental School UNICAMP Piracicaba SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Morais Dornelas Bezerra","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Periodontology. Piracicaba Dental School UNICAMP Piracicaba SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Altair Antoninha","family":"Del Bel Cury","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Periodontology. Piracicaba Dental School UNICAMP Piracicaba SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.8.1482"},{"issue":"4","key":"e_1_2_7_3_1","first-page":"260","article-title":"Daytime sleepiness: more than just Obstructive Sleep Apnea (OSA)","volume":"108","author":"Ferini\u2010Strambi L","year":"2017","journal-title":"Med del Lav"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psc.2006.09.004"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12829"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12162"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910808700917"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.4858"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2004.04.002"},{"key":"e_1_2_7_10_1","first-page":"108","article-title":"Europe PMC funders group meta\u2010analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea\u2010hypopnoea","author":"Sharples LD","year":"2017","journal-title":"Sleep Med Rev"},{"issue":"4","key":"e_1_2_7_11_1","first-page":"CD004435","article-title":"Oral appliances for obstructive sleep apnoea","author":"Lim J","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2005.01467.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsmc.2009.04.006"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(82)90142-0"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/28.11.1381"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.4.1065"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000156861"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-003-0119-3"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200311-1571OC"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-009-0298-9"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.113.3.707"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.116.6.1511"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0722.2002.11178.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2842.2003.01134.x"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2000.0275"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20649"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.2.244"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjoor.12898","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12898","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joor.12898","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.12898","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T09:04:13Z","timestamp":1694250253000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.12898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,6]]},"references-count":26,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1111\/joor.12898"],"URL":"https:\/\/doi.org\/10.1111\/joor.12898","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"type":"print","value":"0305-182X"},{"type":"electronic","value":"1365-2842"}],"subject":[],"published":{"date-parts":[[2019,10,6]]},"assertion":[{"value":"2018-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}