{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T20:30:17Z","timestamp":1786307417563,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T00:00:00Z","timestamp":1604620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oral myofunctional therapy (MFT) is an effective treatment for mild\u2010to\u2010moderate obstructive sleep apnoea (OSA) in middle\u2010aged patients. However, few reports have described its use in elderly patients with moderate and severe OSA. Moreover, no studies have examined the relationship between changes in tongue pressure with MFT and the severity of OSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We conducted an interventional study using MFT to evaluate the effect of MFT on middle\u2010to\u2010senior\u2010aged patients with moderate or severe OSA and compared changes in apnoea\u2010hypopnea index (AHI) and tongue pressure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010two OSA patients (\u226545\u00a0years) treated with continuous positive airway pressure (CPAP) were included. MFT was performed in parallel with CPAP. Three days after CPAP discontinuation, polysomnographies were performed and tongue pressures were measured before and after MFT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients were 69.3\u00a0\u00b1\u00a01.5\u00a0years old. After 6\u00a0months of MFT, AHI decreased significantly from 34.7 to 29.0\/h (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.03), while tongue pressure significantly increased from 35.9 to 45.6\u00a0kPa (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.01). Seven patients (22%), including 6 of the 12 patients with moderate OSA (50%), experienced successful CPAP discontinuation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>MFT can be a useful intervention even among middle\u2010aged to elderly patients with OSA. Increased tongue pressure may have contributed to the AHI improvement.<\/jats:p>\n                    <jats:p>\n                      Clinical trials: Trial registration at\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.umin.ac.jp\">www.umin.ac.jp<\/jats:ext-link>\n                      UMIN000027547.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.13119","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T16:01:57Z","timestamp":1603209717000},"page":"176-182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Efficacy of oral myofunctional therapy in middle\u2010aged to elderly patients with obstructive sleep apnoea treated with continuous positive airway pressure"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0655-4760","authenticated-orcid":false,"given":"Mayumi","family":"Suzuki","sequence":"first","affiliation":[{"name":"Division of Comprehensive Sleep Medicine Tokyo Women\u2019s Medical University  Tokyo Japan"},{"name":"Department of Cardiology Tokyo Women\u2019s Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Tokyo Women\u2019s Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Akagi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Tokyo Women\u2019s Medical University  Tokyo 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Organization Kyoto Medical Center  Fukakusa Japan"},{"name":"Clinical Research Institute National Hospital Organization Yokohama Medical Center  Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsumi","family":"Satoya","sequence":"additional","affiliation":[{"name":"Division of Comprehensive Sleep Medicine Tokyo Women\u2019s Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Inoue","sequence":"additional","affiliation":[{"name":"Division of Comprehensive Sleep Medicine Tokyo Women\u2019s Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihisa","family":"Tatsuta","sequence":"additional","affiliation":[{"name":"Division of Comprehensive Sleep Medicine Tokyo Women\u2019s Medical University  Tokyo 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