{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T01:42:31Z","timestamp":1785116551649,"version":"3.55.0"},"reference-count":67,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T00:00:00Z","timestamp":1610496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To systematically review the effects of surgical mandibular advancement (SMA) regarding changes of the upper airways in adult patients with skeletal Class II malocclusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Five electronic databases were searched up to April 2020. Human studies focusing on the morphology and dimension of the upper airways after SMA were included. \u2018Quality assessment for Before\u2010After (Pre\u2010Post) Studies\u2019 was used to assess the risk of bias of the individual studies. Standard mean differences (SMD) with 95% confidence intervals (CI) were calculated for random effect model meta\u2010analysis. The certainty of evidence was assessed using the GRADE tool.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty cohort studies of only treated patients without control group were eligible for qualitative synthesis, of which 17 were used for quantitative synthesis. Very low certainty of evidence indicated that SMA resulted in significant increase of the volume and of the smallest cross\u2010sectional area (SMC) of the nasopharynx (volume SMD: 1.43, CI: 0.62, 2.24, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a087.8%; SMC SMD: 1.53, CI: 0.59, 2.47, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a090.5%) and oropharynx (volume SMD: 1.36, CI: 0.37,2.35, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.007, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a092.1%; SMC SMD: 1.21, CI: 0.11,2.32, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.032, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a093.1%). Significant augmentation of the distances between the posterior pharynx wall and the uvala (SMD: 0.73, CI: 0.46,0.98, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a072.7%), the posterior border of the tongue (SMD: 0.52, CI: 0.21,0.84, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>: 60.5%), the gonion (SMD: 1.24, CI: 0.56,1.91, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a088.8%) and the epiglottis (SMD: 0.40, CI: 0.06,0.74, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.033; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a084.8%) were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Weak evidence suggests enlargement of the upper airways of adult Class II subjects following SMA, with major increases in the oropharynx.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.13140","type":"journal-article","created":{"date-parts":[[2020,12,30]],"date-time":"2020-12-30T21:53:03Z","timestamp":1609365183000},"page":"210-232","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of surgical mandibular advancement on the upper airways of adult class II patients: A systematic review with meta\u2010analysis"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2588-2949","authenticated-orcid":false,"given":"Rosaria","family":"Bucci","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences University of Naples Federico II Naples Italy"},{"name":"Department of Medicine, Surgery and Dentistry \u201cScuola Medica Salernitana\u201d University of Salerno Salerno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Rongo","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences University of Naples Federico II Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Bucci","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences University of Naples Federico II Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Valletta","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences University of Naples Federico II Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambrosina","family":"Michelotti","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences University of Naples Federico II Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"D\u2019Ant\u00f2","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Oral Sciences University of Naples Federico II Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12794"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.23804\/ejpd.2018.19.03.2"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1073\u20108746(96)80048\u2010x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjz081"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjz076"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12295"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cxom.2015.10.005"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2008.01.020"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2011.02.015"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejwf.2012.06.001"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2013.01.015"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12029"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2007.06.020"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.2.9908123"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2016.07.002"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2010.02.011"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034519885644"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/22.4.353"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.2319\/030210\u2010125.1"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.180"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.2319\/083117\u2010587.1"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2019.03.021"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2017.04.009"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25505"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp\u20102019\u2010000402"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.02.138"},{"key":"e_1_2_9_28_1","first-page":"359","article-title":"Evaluation of PICO as a knowledge representation for clinical questions","volume":"2006","author":"Huang X","year":"2006","journal-title":"AMIA. Annu Symp proceedings AMIA Symp"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000100"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643\u2010016\u20100384\u20104"},{"key":"e_1_2_9_31_1","unstructured":"NIH.Quality Assessment Tool for Before\u2010After (Pre\u2010Post)Studies With No Control Group. https:\/\/www.nhlbi.nih.gov\/health\u2010topics\/study\u2010quality\u2010assessment\u2010tools. Published. 2014."},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.09.011"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2019.07.024"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2019.09.001"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056\u2010017\u20100101\u20105"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2015.10.006"},{"issue":"1","key":"e_1_2_9_37_1","first-page":"5","article-title":"Importance and calculation of pharyngeal spaces and hyoid position before and after orthognathic surgery","volume":"5","author":"Yadav D","year":"2015","journal-title":"Adv Hum Biol"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.4025\/actascihealthsci.v37i2.21287"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056\u2010012\u20100132\u2010x"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e318270fafd"},{"issue":"2","key":"e_1_2_9_41_1","first-page":"147","article-title":"The impact of mandibular advancement on the upper airway patterns \u2013 cephalometric study","volume":"108","author":"Foltan R","year":"2007","journal-title":"Prague Med Rep"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1415-54192007000500015"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.07.019"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/22.4.367"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12663\u2010019\u201001266\u20101"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2019.07.006"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2018.03.023"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12264"},{"key":"e_1_2_9_49_1","article-title":"Changes in head posture, hyoid bone position and airway dimensions after orthognatic surgery","volume":"17","author":"Azevedo WR","year":"2018","journal-title":"Brazilian J Oral Sci"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2017.10.022"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016357.2016.1252851"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2017.02.021"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr\/31005700"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1179\/ortho.27.3.235"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.2.375"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/21.4.357"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/21.4.345"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12321"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2005.05.001"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)31254-8"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601\u20106343.2010.01482.x"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.03.015"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjw079"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjy058"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12348"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.5037\/jomr.2016.7101"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2008.03.006"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2002.0279"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.13140","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joor.13140","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.13140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T13:37:47Z","timestamp":1692452267000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.13140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,13]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/joor.13140"],"URL":"https:\/\/doi.org\/10.1111\/joor.13140","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,13]]},"assertion":[{"value":"2020-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}