{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T01:27:44Z","timestamp":1792891664580,"version":"4.5.0"},"reference-count":56,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,8,21]],"date-time":"2021-08-21T00:00:00Z","timestamp":1629504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81660189"],"award-info":[{"award-number":["81660189"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the efficacy of low\u2010level laser therapy (LLLT) with different wavelengths and transcutaneous electric nerve stimulation (TENS) and explore the optimal wavelength range of laser application in the treatment of pain caused by temporomandibular disorders (TMD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An electronic search on PubMed, Cochrane Library, Embase, Scopus and Web of Science was undertaken to identify the randomised clinical trials (RCTs) published from database inception to 16 April 2021, aiming to compare the effects of LLLT with different wavelengths (632.8\u2013672\u00a0nm, 780\u2013904\u00a0nm, and 910\u20131100\u00a0nm) or TENS or placebo group on TMD patients pain reduction. In addition, manual search of the studies was performed. The reviewers assessed the risk of bias of individual studies with the Cochrane risk of bias tool and excluded the RCTs with a high risk of bias in any field. Meanwhile, the reviewers, after performing the network meta\u2010analysis, assessed the quality of evidence, which contributed to network estimate via the GRADE framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010seven RCTs with 969 patients with TMD were included. In the meta\u2010analysis, all treatment groups showed an overall improvement in pain scores, when compared with the placebo group. LLLT with wavelength ranging from 910\u00a0nm to 1100\u00a0nm produced more pain relief in the visual analogue scale (VAS) immediately after treatment [mean difference (MD)\u00a0=\u00a04.68, 95% confidence interval (CI):(3.08,6.28)]. After one\u2010month follow\u2010up, LLLT with wavelength ranging from 910\u00a0nm to 1100\u00a0nm also showed superior pain\u2010relieving effects [MD\u00a0=\u00a03.61, 95% CI: (\u22121.77, 8.99)]. However, no significant difference was observed. Based on the SUCRA ranking, L3 ranked first immediately after treatment and 1\u00a0month later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of the meta\u2010analysis showed the LLLT had better short\u2010term efficacy than TENS in the treatment of pain caused by TMD. Better results can be achieved with higher wavelengths. Therefore, we recommended to treat TMD using LLLT with wavelength ranging from 910\u00a0nm to 1100\u00a0nm.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.13230","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T14:01:59Z","timestamp":1626876119000},"page":"138-149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Comparative effectiveness of low\u2010level laser therapy with different wavelengths and transcutaneous electric nerve stimulation in the treatment of pain caused by temporomandibular disorders: A systematic review and network meta\u2010analysis"],"prefix":"10.1111","volume":"49","author":[{"given":"Hui","family":"Ren","sequence":"first","affiliation":[{"name":"Department of Temporomandibular joint and Occlusion School\/Hospital of Stomatology Lanzhou University Lanzhou 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