{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T23:34:22Z","timestamp":1793316862576,"version":"4.5.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oxygen saturation indices show a strong correlation with long\u2010term health outcomes. Nonetheless, evidence on the relationship between reduction in respiratory events and increase in oxygenation levels following oral appliance (OA) treatment is scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To verify the relationship between reduction in the apnoea\u2010hypopnoea index (AHI) and oxygen saturation levels following OA treatment, we have conducted an evaluation of polysomnography (PSG) and clinical parameters associated with the improvement of oxygen desaturation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      OSA patients (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a048) who received an OA and had pre\u2010 and post\u2010treatment PSG were classified into three responder groups according to the change in AHI and min O\n                      <jats:sub>2<\/jats:sub>\n                      post\u2010treatment: responder\n                      <jats:sub>AHIonly<\/jats:sub>\n                      (decrease in AHI of \u226550% but increase in min O\n                      <jats:sub>2<\/jats:sub>\n                      \u00a0level of &lt;4% or decrease); responder\n                      <jats:sub>MinO2only<\/jats:sub>\n                      (increase in min O\n                      <jats:sub>2<\/jats:sub>\n                      \u00a0level of \u22654% but decrease in AHI &lt;50% or increase) and responder\n                      <jats:sub>Congruous<\/jats:sub>\n                      (decrease in AHI of \u226550% and increase in min O\n                      <jats:sub>2<\/jats:sub>\n                      \u00a0level of \u22654%). Various demographic and PSG variables were statistically compared among groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 26 (54.17%) responder\n                      <jats:sub>AHIonly<\/jats:sub>\n                      , 9 (18.75%) responder\n                      <jats:sub>MinO2only<\/jats:sub>\n                      and 13 (27.08%) responder\n                      <jats:sub>Congruous<\/jats:sub>\n                      . Pre\u2010treatment min O\n                      <jats:sub>2<\/jats:sub>\n                      was significantly lower in responder\n                      <jats:sub>MinO2only<\/jats:sub>\n                      . A higher pre\u2010treatment min O\n                      <jats:sub>2<\/jats:sub>\n                      \u00a0showed a significant correlation with a smaller amount of change in mean O\n                      <jats:sub>2<\/jats:sub>\n                      (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a0\u2212.486) and min O\n                      <jats:sub>2<\/jats:sub>\n                      (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a0\u2212.764) with treatment. Pre\u2010treatment min O\n                      <jats:sub>2<\/jats:sub>\n                      \u00a0showed the strongest ability to predict those who would show a \u22654% min O\n                      <jats:sub>2<\/jats:sub>\n                      increase following treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Certain patients do not show sufficient decrease in hypoxaemia in spite of the improvement in AHI. Pre\u2010treatment min O\n                      <jats:sub>2<\/jats:sub>\n                      \u00a0should be considered in OA treatment planning regarding its close relation to improvements in oxygenation levels with treatment.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.13316","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T03:37:19Z","timestamp":1646969839000},"page":"633-643","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Disparities in oxygen saturation and hypoxic burden levels in obstructive sleep apnoea patient\u2019s response to oral appliance treatment"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0625-7021","authenticated-orcid":false,"given":"Ji Woon","family":"Park","sequence":"first","affiliation":[{"name":"Department of Oral Health Sciences Faculty of Dentistry University of 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