{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:15:17Z","timestamp":1789020917713,"version":"build-2803163510"},"reference-count":49,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Several solutions are available for the rehabilitation of edentulous jaws. Each treatment option is characterised by specific advantages and drawbacks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this research was to perform a cost\u2010effectiveness (CE) analysis of the main rehabilitative solutions of totally edentulous mandibles.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Decision tree models were built using TreeAge Pro Healthcare 2021 software to compare the following strategies: Conventional Denture (CD), Overdenture retained by two implants (OD\u20102), Overdenture retained by a bar on two implants (ODbar), Overdenture retained by 4 mini\u2010implants (ODmini) and Fixed denture supported by 4 implants (FD). Costs were estimated using data from public rate tables. Effectiveness measures were obtained from a meta\u2010analysis of literature data, normalising the different scales in 0\u20131 range. A value of 30\u2009000\u20ac per 1 normalised utility points was set as threshold of willingness to pay (WTP). Probabilistic sensitivity analysis (PSA) with 1000 Monte Carlo Simulations was performed to characterise uncertainty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Total costs ranged between 1804,40\u20ac for CD and 10\u2009008,80\u20ac for FD rehabilitations, with an effectiveness of 0,69 and 0,95 normalised points (0\u20131 scale) for the two solutions. The ODbar resulted to be the most CE strategy at the established WTP value, with the highest Net Monetary Benefit (22\u2009001,20\u20ac), followed by the OD\u20102 rehabilitation (21\u2009866,80\u20ac). PSA analysis confirmed the dominance of OD\u20102 and ODbar strategies, confirming a net separation from the other alternatives.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>OD stabilised by 2 implants could represent a good rehabilitative solution for patients with edentulous mandible, being a good trade\u2010off in terms of costs and effectiveness. Nevertheless, a standardised measure of oral health\u2010related quality of life is needed to obtain more reliable results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.13423","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T04:37:55Z","timestamp":1674794275000},"page":"400-409","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Cost\/effectiveness analysis of treatment options for the rehabilitation of the total edentulous mandible"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2153-0778","authenticated-orcid":false,"given":"Khrystyna","family":"Zhurakivska","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Luciano","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5080-5921","authenticated-orcid":false,"given":"Vito Carlo Alberto","family":"Caponio","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6127-6105","authenticated-orcid":false,"given":"Lucio","family":"Lo\u00a0Russo","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo Lo","family":"Muzio","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Mascitti","sequence":"additional","affiliation":[{"name":"Department of Clinical Specialistic and Dental Sciences Marche Polytechnic University  Ancona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Troiano","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1922\/IDJ_2184Polzer13"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-016-0256-2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.2003.com122.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/dj7020049"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1563\/aaid-joi-D-17-00210"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-021-04213-y"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.12.024"},{"issue":"4","key":"e_1_2_10_9_1","first-page":"285","article-title":"Immediate loading of full\u2010arch fixed prostheses supported by axial and tilted implants for the treatment of edentulous atrophic mandibles","volume":"41","author":"Agliardi E","year":"2010","journal-title":"Quintessence Int"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13312"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13027"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cre2.347"},{"key":"e_1_2_10_13_1","unstructured":"Istituto Nazionale di Statistica. 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