{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T20:39:33Z","timestamp":1783543173604,"version":"3.55.0"},"reference-count":51,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T00:00:00Z","timestamp":1681171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Obstructive sleep apnoea (OSA) is characterized by repetitive narrowing and collapse of pharyngeal airway during sleep, leading to apnoea or hypopnoea. In this context, myofunctional therapy and myofascial release might be effective, despite the literature on the combination of these approaches is still scarce.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This randomized controlled trial aimed to assess the efficacy of oro\u2010facial myofunctional therapy combined with myofascial release in terms of functioning in patients with mild OSA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients aged from 40 to 80\u2009years with diagnosis of mild OSA were randomly allocated into intervention group (oro\u2010facial myofunctional therapy plus myofascial release) and control group (only oro\u2010facial myofunctional therapy). At the baseline (T0), after 4\u2009weeks (T1), and after 8\u2009weeks (T2), the following outcomes were assessed: apnoea\/hypopnoea index (AHI), average oxygen saturation (SpO<jats:sub>2<\/jats:sub>), sleep time spent with oxygen saturation\u2009&lt;\u200990% (T90), snoring index, and Pittsburgh Sleep Quality Index (PSQI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of the 60 patients enrolled, 28 (aged 61.46\u2009\u00b1\u20098.74\u2009years) complete the treatment in the intervention group and 24 (aged 60.42\u2009\u00b1\u20096.61\u2009years) in the control group. There were no significant differences in AHI between groups. A significant difference was reported for \u0394T0\u2013T1 SpO2 (<jats:italic>p<\/jats:italic>\u2009=\u2009.01), T90 (<jats:italic>p<\/jats:italic>\u2009=\u2009.030), \u0394T0\u2013T1 and \u0394T0\u2013T2 snoring index (<jats:italic>p<\/jats:italic>\u2009=\u2009.026 and &lt;.001 respectively), and \u0394T0\u2013T1 and \u0394T0\u2013T2 Pittsburgh Sleep Quality Index (<jats:italic>p<\/jats:italic>\u2009=\u2009.003 and &lt;.001 respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Taken together, a combination of oro\u2010facial myofunctional therapy and myofascial release showed a potential treatment for sleep quality in patients with mild OSA. Future studies are necessary to better investigate the role of these interventions in OSA patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/joor.13456","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T12:09:14Z","timestamp":1680523754000},"page":"555-565","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Efficacy of orofacial myofunctional therapy combined with myofascial release in patients with mild obstructive sleep apnoea: a randomized controlled trial"],"prefix":"10.1111","volume":"50","author":[{"given":"Teresa","family":"Paolucci","sequence":"first","affiliation":[{"name":"Department of Medical and Oral Sciences and Biotechnologies University \u201cG. D'Annunzio\u201d of Chieti  Chieti\u2010Pescara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Ferrillo","sequence":"additional","affiliation":[{"name":"Department of Health Sciences University of Catanzaro \u201cMagna Graecia\u201d  Catanzaro Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia","family":"Pezzi","sequence":"additional","affiliation":[{"name":"Specialistic Rehabilitation Department ASST Cremona  Cremona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Agostini","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Histology, Forensic Medicine and Orthopaedics \u201cSapienza\u201d University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Di\u00a0Matteo","sequence":"additional","affiliation":[{"name":"Department of Medical and Oral Sciences and Biotechnologies University \u201cG. D'Annunzio\u201d of Chieti  Chieti\u2010Pescara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Prosperi","sequence":"additional","affiliation":[{"name":"Department of Pneumology and Respiratory Physiopathology S. Spirito Hospital  Pescara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Mangone","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Histology, Forensic Medicine and Orthopaedics \u201cSapienza\u201d University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bernetti","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Histology, Forensic Medicine and Orthopaedics \u201cSapienza\u201d University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Spacone","sequence":"additional","affiliation":[{"name":"Department of Pneumology and Respiratory Physiopathology S. 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