{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:52:09Z","timestamp":1772160729967,"version":"3.50.1"},"reference-count":61,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T00:00:00Z","timestamp":1711324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Obstructive sleep apnoea syndrome (OSAS) has garnered increasing attention in recent years due to its potential association with cancer. This systematic review and meta\u2010analysis aimed to assess the prevalence of OSAS in cancer patients through a comprehensive analysis of existing literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This systematic review and meta\u2010analysis, conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) protocol, aimed to evaluate the prevalence of OSAS in cancer patients. A comprehensive search of electronic databases was performed to identify relevant studies published up to September 2021. Eligible studies reporting on the prevalence of OSAS in cancer patients, encompassing various study designs, were included in the analysis. Pooled estimates of the odds ratios (OR) with 95% confidence intervals (CIs) were calculated using a random effects model. Heterogeneity among the studies was assessed using the I\n                      <jats:sup>2<\/jats:sup>\n                      statistic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventeen studies fulfilled the inclusion criteria and were subsequently included in the review. The prevalence of OSAS in cancer patients was estimated to have an overall OR of 0.80 (95% CI: 0.75\u20130.85). In comparison with non\u2010cancer patients, cancer patients had a statistically significant greater risk of OSAS, as indicated by the total estimated RR for the prevalence of OSAS in cancer patients, which was 0.89 (95% CI: 0.86\u20130.92). Nonetheless, there was a significant amount of heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200996%) among the studies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The overall data analysed in this review indicates that patients with cancer had far reduced likelihood of developing OSAS than individuals without cancer. However, the significant variation across the included studies highlights the need for additional investigation to fully clarify the complex association between OSAS and cancer incidence. These results emphasise how critical it is to identify OSAS as a possible comorbidity in cancer patients, one that should be taken into account for clinical management and ongoing research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.13681","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:28:46Z","timestamp":1711412926000},"page":"1236-1249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of obstructive sleep apnoea syndrome in oncological patients: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"51","author":[{"given":"Mohammed Abdul","family":"Kader","sequence":"first","affiliation":[{"name":"Department of Restorative Dental Science, College of Dentistry King Khalid University Abha  Abha Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Sainudeen","sequence":"additional","affiliation":[{"name":"Department of Restorative Dental Science, College of Dentistry King Khalid University Abha  Abha Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdul Ahad Ghaffar","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery King Khalid University College of Dentistry  Abha Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suraj","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Restorative Dental Science, College of Dentistry King Khalid University Abha  Abha Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Ronsivalle","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Medical\u2010Surgical Specialties, School of Dentistry University of Catania  Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9494-6942","authenticated-orcid":false,"given":"Maria Maddalena","family":"Marrapodi","sequence":"additional","affiliation":[{"name":"Department of Woman, Child and General and Specialized Surgery, Obstetrics and Gynecology Unit, Largo Madonna delle Grazie 1 University of Campania \"Luigi Vanvitelli\"  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Cicci\u00f9","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Medical\u2010Surgical Specialties, School of Dentistry University of Catania  Catania Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8309-1272","authenticated-orcid":false,"given":"Giuseppe","family":"Minervini","sequence":"additional","affiliation":[{"name":"Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University  Chennai India"},{"name":"Multidisciplinary Department of Medical\u2010Surgical and Dental Specialties University of Campania \u201cLuigi Vanvitelli\u201d  Naples Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2021.06.042"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000028930"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01496-3"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57111174"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2006.06.037"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-020-0549-z"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/prosthesis4010007"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/prosthesis4040047"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/prosthesis4040053"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/prosthesis4040054"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/prosthesis4010010"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/prosthesis4040044"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.21037\/apm-22-972"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.11607\/ofph.3176"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199304293281704"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2016.07.002"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00234-2016"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2005.10.033"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00036.2018"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jebdp.2022.101786"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13573"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13497"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13535"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-0500"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2015.04.014"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12427"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.7.378"},{"key":"e_1_2_9_29_1","first-page":"771","article-title":"Clinical trial with bromelain in third molar exodontia","volume":"14","author":"Inchingolo F","year":"2010","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2021.0546"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.13105\/wjma.v5.i4.80"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1159\/000486577"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201209-1671OC"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.05.026"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2019.02.016"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.11.782"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-55551-7"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.102725"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.6004"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819900487"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.140238"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2016.07.061"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-019-2075-6"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3600"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.01.020"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8050381"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmedr.2019.100886"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25507"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13473"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof7060476"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10024-2130"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.12816\/0003147"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12531"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13450"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13559"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13472"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.09.006"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.15-0634"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-3014"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2017.08.008"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.04.029"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.3030"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.13681","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T23:46:40Z","timestamp":1717631200000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.13681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,25]]},"references-count":61,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/joor.13681"],"URL":"https:\/\/doi.org\/10.1111\/joor.13681","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JOOR.13681\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v2\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.13681\/v1\/review4","asserted-by":"object"}]},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,25]]},"assertion":[{"value":"2023-10-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}