{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:33:01Z","timestamp":1780446781306,"version":"3.54.1"},"reference-count":8,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To critically evaluate the classification of Burning Mouth Syndrome (BMS) into \u2018peripheral\u2019 or \u2018central\u2019 subtypes based on short\u2010term pain relief (\u2265\u20091 cm on the Visual Analogue Scale, VAS) following lingual nerve block, and to explore how quantitative sensory testing (QST) might refine BMS diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>We reviewed two recent publications by Yang et\u00a0al. investigating conditioned pain modulation (CPM) and lingual nerve block efficacy in BMS. We examined their reliance on immediate VAS reductions, sample size, QST findings, and adherence to International Classification of Headache Disorders (ICHD\u20103) criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Yang et\u00a0al. reported diminished CPM responses, particularly in the wind\u2010up ratio, among patients classified as central BMS, and highlighted short\u2010term pain relief exclusively in the peripheral subtype. However, categorising patients solely by a \u2265\u20091 cm VAS reduction may oversimplify the multifactorial nature of BMS, especially when QST findings did not consistently distinguish between groups. Additionally, a small sample size (\n                      <jats:italic>n<\/jats:italic>\n                      =\u200920) could limit generalisability and obscure subtle pathophysiological differences.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although Yang et\u00a0al. appropriately applied standard diagnostic guidelines, we recommend integrating subjective (e.g., McGill Pain Questionnaire, Pain Catastrophizing Scale) and objective (e.g., QST, CPM) assessments to capture the complex interplay of peripheral and central mechanisms in BMS. These findings underscore the difficulty of reducing BMS to a strict dichotomy and highlight the need for nuanced, multidimensional approaches. Larger, more diverse cohorts and multidimensional evaluations may improve patient stratification and treatment targeting, ultimately enhancing clinical outcomes for individuals with BMS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.14031","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:29:14Z","timestamp":1747268954000},"page":"1160-1163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Challenging the \u2018Central vs. Peripheral\u2019 Classification in Burning Mouth Syndrome: A Critical Analysis of Yang et\u00a0al.'s Studies"],"prefix":"10.1111","volume":"52","author":[{"given":"Takayuki","family":"Suga","sequence":"first","affiliation":[{"name":"Department of Psychosomatic Dentistry Graduate School of Medical and Dental Sciences, Institute of Science Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Toyofuku","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Dentistry Graduate School of Medical and Dental Sciences, Institute of Science Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13876"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13877"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3516"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpain.2024.1349847"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.11.016"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2024.07.007"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102419893823"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/25158163251339141"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.14031","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joor.14031","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.14031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T14:47:55Z","timestamp":1772981275000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.14031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,14]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/joor.14031"],"URL":"https:\/\/doi.org\/10.1111\/joor.14031","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JOOR.14031\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.14031\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.14031\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.14031\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.14031\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.14031\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.14031\/v2\/response1","asserted-by":"object"}]},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,14]]},"assertion":[{"value":"2024-11-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}