{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T05:05:00Z","timestamp":1780031100048,"version":"3.53.1"},"reference-count":48,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Study Objectives<\/jats:title>\n                    <jats:p>Obstructive sleep apnoea (OSA) is a prevalent sleep disorder with significant health implications. While complete edentulism has been associated with an increased OSA risk, the relationship with partial edentulism remains unclear. This study aimed to investigate the role of dental formula in OSA severity and mandibular advancement device (MAD) therapy outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study initially included 560 patients diagnosed with OSA by polysomnography (PSG). A subset of 75 patients was selected for analysis based on predefined inclusion criteria. Dental parameters were assessed using baseline orthopantomograms. Objective treatment outcomes were evaluated using baseline PSG and repeat PSG with MAD after 3 months of therapy. Differences in OSA severity and MAD treatment outcomes were analysed, and dental parameters were correlated between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The median baseline apnoea\u2013hypopnoea index (AHI) significantly reduced from 27.82\u2009\u00b1\u200916.77 to 15.51\u2009\u00b1\u200913.33 following MAD therapy. Partial edentulism parameters did not differ significantly or correlate with baseline OSA severity. However, a correlation was observed between the number of missing teeth and reassessed AHI (rAHI), and an inverse correlation between the masticatory coefficient and rAHI was also noted. Mandibular edentulism\u2014primarily unilateral or bilateral posterior\u2014was positively correlated with MAD treatment outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study demonstrates a correlation between edentulism parameters and MAD treatment outcomes in patients with OSA. Collaboration between dentists and sleep medicine specialists is crucial for comprehensive OSA management, including oral health assessment.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial Registration:<\/jats:bold>\n                      After evaluation and validation by the data protection officer and according to the General Data Protection Regulation, this study met all the criteria and was registered in the register of data study of the Toulouse University Hospital (Register Number: RnIPH 2023\u201381) and covered by the MR\u2010004 (CNIL Number: 2206723 v 0).\n                    <\/jats:p>\n                    <jats:p>This study was approved by Toulouse University Hospital and confirmed that ethical requirements were fully met in the above report.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70006","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T11:45:46Z","timestamp":1753184746000},"page":"2114-2123","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Does the Dental Formula Predict Therapy Outcomes of Obstructive Sleep Apnoea Treated With a Mandibular Advancement Device ? A Retrospective Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7945-757X","authenticated-orcid":false,"given":"Constance","family":"Cuny","sequence":"first","affiliation":[{"name":"Laboratoire Centre d'Anthropobiologie et de G\u00e9nomique de Toulouse Universit\u00e9 Paul Sabatier  Toulouse France"},{"name":"Health Faculty\u2014Dentistry Department, Toulouse Institute of Oral Medicine and Science CHU de Toulouse  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7373-2657","authenticated-orcid":false,"given":"Philippe","family":"Kemoun","sequence":"additional","affiliation":[{"name":"Health Faculty\u2014Dentistry Department, Toulouse Institute of Oral Medicine and Science CHU de Toulouse  Toulouse France"},{"name":"RESTORE Research Center Universit\u00e9 de Toulouse, INSERM 1301, CNRS 5070, EFS, ENVT  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1011-2212","authenticated-orcid":false,"given":"Florent","family":"Destruhaut","sequence":"additional","affiliation":[{"name":"Health Faculty\u2014Dentistry Department, Toulouse Institute of Oral Medicine and Science CHU de Toulouse  Toulouse France"},{"name":"CERPOP UMR 1295, BIOETHICS, Inserm Universit\u00e9 de Toulouse Paul Sabatier  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coraline","family":"Sipra","sequence":"additional","affiliation":[{"name":"Health Faculty\u2014Dentistry Department, Toulouse Institute of Oral Medicine and Science CHU de Toulouse  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0579-341X","authenticated-orcid":false,"given":"Mathieu","family":"Marty","sequence":"additional","affiliation":[{"name":"Health Faculty\u2014Dentistry Department, Toulouse Institute of Oral Medicine and Science CHU de Toulouse  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0727-7745","authenticated-orcid":false,"given":"Delphine","family":"Comtesse\u2010Maret","sequence":"additional","affiliation":[{"name":"Laboratoire Centre d'Anthropobiologie et de G\u00e9nomique de Toulouse Universit\u00e9 Paul Sabatier  Toulouse France"},{"name":"Health Faculty\u2014Dentistry Department, Toulouse Institute of Oral Medicine and Science CHU de Toulouse  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3229-7932","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Vaysse","sequence":"additional","affiliation":[{"name":"Laboratoire Centre d'Anthropobiologie et de G\u00e9nomique de Toulouse Universit\u00e9 Paul Sabatier  Toulouse France"},{"name":"Health Faculty\u2014Dentistry Department, Toulouse Institute of Oral Medicine and Science CHU de Toulouse  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13020502"},{"key":"e_1_2_10_3_1","volume-title":"International Classification of Sleep Disorders","author":"American Academy of Sleep Medicine","year":"2014"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14\u20100970"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010012\u20100760\u2010y"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2014.07.003"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01618\u20102015"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2023.02.005"},{"issue":"1","key":"e_1_2_10_9_1","doi-asserted-by":"crossref","first-page":"48","DOI":"10.65314\/2218-0885.1181","article-title":"Relationship Between Edentulism and Sleep Apnea: A Systematic Review of the Literature","volume":"12","author":"Ammar S.","year":"2021","journal-title":"International Arab Journal of Dentistry"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1465\u20109921\u20107\u20108"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/1119\u20103077.154203"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19095517"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010015\u20101310\u2010z"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010020\u201002131\u2010z"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2020.02.012"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807\u20103107BOR\u20102017.vol31.0037"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.4041\/kjod.2015.45.6.308"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13392"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2172"},{"key":"e_1_2_10_20_1","volume-title":"Proth\u00e8se Amovible Partielle","author":"Schittly J.","year":"2019"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20102600(19)30198\u20105"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010023\u201002810\u20107"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2016.07.002"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2009.10.005"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741\u20102358.2010.00426.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745\u20106215\u201015\u2010358"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752\u20107325.2004.tb02749.x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010015\u20101256\u20101"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1590\/0004\u2010282X\u2010ANP\u20102020\u20100368"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2018.07.020"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102017\u2010018383"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010011\u20100587\u20109"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010016\u20101851\u2010y"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12152"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jds.2011.02.002"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.4.2005022"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2018.9.22750"},{"key":"e_1_2_10_38_1","first-page":"516969","article-title":"Cephalometric Evaluation of the Effect of Complete Dentures on Retropharyngeal Space and Its Effect on Spirometric Values in Altered Vertical Dimension","volume":"2011","author":"Gupta P.","journal-title":"ISRN Dentistry"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2020.1686978"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.2739\/kurumemedj.59.5"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010018\u20101643\u20105"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2007.01.009"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2020.16.2.215"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2021.11.001"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910808700917"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2012.0066"},{"issue":"3","key":"e_1_2_10_47_1","first-page":"15","article-title":"Factors Related to the Efficacy of an Adjustable Oral Appliance for the Treatment of Obstructive Sleep Apnea","volume":"3","author":"Liu Y.","year":"2000","journal-title":"Chinese Journal of Dental Research"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1067\/mod.2001.118782"},{"issue":"3","key":"e_1_2_10_49_1","first-page":"594","article-title":"Three\u2010Dimensional Movement of Posterior Teeth After Losing the Interproximal and Occlusal Contacts in Adults","volume":"53","author":"Liu X. Q.","year":"2021","journal-title":"Beijing Da Xue Xue Bao. Yi Xue Ban"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.70006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joor.70006","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.70006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T04:45:39Z","timestamp":1780029939000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.70006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,22]]},"references-count":48,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/joor.70006"],"URL":"https:\/\/doi.org\/10.1111\/joor.70006","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JOOR.70006\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.70006\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.70006\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.70006\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JOOR.70006\/v2\/review1","asserted-by":"object"}]},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,22]]},"assertion":[{"value":"2024-09-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}