{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:33Z","timestamp":1787015553229,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Temporomandibular disorders (TMD) are complex conditions influenced by multiple factors, including dietary habits. This study aimed to explore the potential causal relationships between dietary patterns and TMD risk using bidirectional Mendelian randomisation (MR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A bidirectional two\u2010sample\n                      <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\n                      analysis was performed to assess the causal effects of 83 dietary habits on\n                      <jats:styled-content style=\"fixed-case\">TMD<\/jats:styled-content>\n                      risk, and vice versa. Five\n                      <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\n                      methods, including inverse variance weighting (\n                      <jats:styled-content style=\"fixed-case\">IVW<\/jats:styled-content>\n                      ), were applied. Associations with\n                      <jats:italic>p<\/jats:italic>\n                      \u2010values &lt;\u20090.05 were considered suggestive of causality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten dietary habits were found to be significantly associated with TMD risk. Protective factors included muesli consumption (OR\u2009=\u20090.53, 95% CI\u2009=\u20090.34\u20130.82,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.00458), fresh fruit intake (OR\u2009=\u20090.73, 95% CI\u2009=\u20090.58\u20130.92,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.00676), decaffeinated coffee (OR\u2009=\u20090.70, 95% CI\u2009=\u20090.54\u20130.91,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.00789), and red wine intake (OR\u2009=\u20090.73, 95% CI\u2009=\u20090.53\u20131.00,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0477). Risk\u2010enhancing factors included frequent consumption of white or brown bread, cornflakes\/frosties, low\u2010fat spreads, and complete sugar avoidance. Reverse MR indicated potential reverse causality for red wine intake (OR\u2009=\u20090.99, 95% CI\u2009=\u20090.97\u20131.00,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.00937).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggest that specific dietary habits may causally influence the risk of TMD. These insights could inform dietary recommendations for TMD prevention and highlight the need for mechanistic and longitudinal studies to validate these associations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70016","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T02:21:20Z","timestamp":1753410080000},"page":"2124-2130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association Between Dietary Habits and the Risk of Temporomandibular Disorders: A Bidirectional Mendelian Randomisation Study"],"prefix":"10.1111","volume":"52","author":[{"given":"Mengzhao","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Stomatology The First Affiliated Hospital of Shenzhen University  Shenzhen China"},{"name":"Health Science Center The First Affiliated Hospital of Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Stomatology The First Affiliated Hospital of Shenzhen University  Shenzhen China"},{"name":"Health Science Center The First Affiliated Hospital of Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Kan","sequence":"additional","affiliation":[{"name":"Department of Stomatology The First Affiliated Hospital of Shenzhen University  Shenzhen China"},{"name":"Health Science Center The First Affiliated Hospital of Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3346-8628","authenticated-orcid":false,"given":"Jinfeng","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Stomatology The First Affiliated Hospital of Shenzhen University  Shenzhen China"},{"name":"Health Science Center The First Affiliated Hospital of Shenzhen University  Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aanat.2021.151882"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2022.08.002"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-036768"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kjms.2018.01.004"},{"issue":"4","key":"e_1_2_10_6_1","first-page":"e37028","article-title":"Prevalence of Temporomandibular Disorders Between 2015\u20102021: A Literature Review","volume":"15","author":"Alrizqi A. 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