{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T13:03:58Z","timestamp":1772283838584,"version":"3.50.1"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:00:00Z","timestamp":1760918400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:00:00Z","timestamp":1760918400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012175","name":"Zhejiang Traditional Chinese Medicine Administration","doi-asserted-by":"publisher","award":["2023ZL525"],"award-info":[{"award-number":["2023ZL525"]}],"id":[{"id":"10.13039\/501100012175","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014759","name":"Medical Scientific Research Foundation of Zhejiang Province, China","doi-asserted-by":"publisher","award":["2023KY988"],"award-info":[{"award-number":["2023KY988"]}],"id":[{"id":"10.13039\/501100014759","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The effectiveness of acupuncture combined with manual therapy for the treatment of temporomandibular disorders myalgia (TMDM) has not been studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the effectiveness of acupuncture combined with manual therapy (MT) for the treatment of TMDM. Furthermore, this study used magnetic resonance imaging (MRI) to observe the influence of acupuncture combined with MT on the thickness, area, and signal intensity ratio (SIR) of the lateral pterygoid muscle (LPM) in patients with TMDM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Sixty\u2010five patients with TMDM were randomly divided into M and A\u2009+\u2009M groups. The M group received manual therapy, and the A\u2009+\u2009M group received acupuncture combined with manual therapy. All of the above treatments were performed once a day, five times a week for two consecutive weeks. The visual analogue scale (VAS), pressure pain threshold (PPT), painless maximum mouth opening (MMO), jaw functional limitation scale (JFLS) score, and thickness, area, and signal intensity ratio of the LPM were determined. Statistical analyses were performed using SPSS version 23.0.\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05 was considered to be statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The VAS and JFLS scores were significantly decreased (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000), while the PPT and MMO values were evidently increased after treatment than before treatment in all groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). After treatment, compared with the M group, the VAS and JFLS scores were reduced (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010), and the PPT and MMO values were increased in the A\u2009+\u2009M group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.041,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006). The overall effective rate in the A\u2009+\u2009M group was significantly higher than the M group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018). Compared with the M group, the area of the upper and lower heads of the LPM increased (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.038,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040), and the signal intensity ratios decreased in the A\u2009+\u2009M group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.032,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Acupuncture combined with MT was superior to MT alone for the treatment of TMDM. Moreover, acupuncture combined with MT significantly increased the area of the LPM and decreased its SIR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.chictr.org.cn\/\">https:\/\/www.chictr.org.cn\/<\/jats:ext-link>\n                      , identifier: ChiCTR2300072801\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70090","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T06:46:07Z","timestamp":1761029167000},"page":"337-347","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Efficacy of Acupuncture Combined With Manual Therapy in the Treatment of Temporomandibular Disorders Myalgia and Observation of the Changes in the Lateral Pterygoid Muscle: A Randomised Clinical Trial"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6371-3724","authenticated-orcid":false,"given":"Jing","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Acupuncture and Rehabilitation Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University  Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7224-2533","authenticated-orcid":false,"given":"Yuxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Radiology Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University  Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangli","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Moxibustion Community Health Service Center  Ningbo Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiamei","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Rehabilitation Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University  Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehua","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Rehabilitation Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University  Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanye","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Rehabilitation Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University  Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhui","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Acupuncture and Rehabilitation Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University  Hangzhou Zhejiang 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