{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:18:40Z","timestamp":1785161920941,"version":"3.55.0"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L232112"],"award-info":[{"award-number":["L232112"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n \n Although females comprise the majority of patients with temporomandibular disorders (\n TMDs<\/jats:styled-content>\n ), few studies have prioritised the influence of sex on symptom severity and impact.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n This cross\u2010sectional study investigated sex\u2010related differences in\n TMD<\/jats:styled-content>\n symptom severity, jaw functional limitation (\n JFL<\/jats:styled-content>\n ) and oral health\u2010related quality of life (\n OHRQoL<\/jats:styled-content>\n ); examined their interrelationships by sex; and identified symptom\u2010specific factors linked to high\n JFL<\/jats:styled-content>\n and low\n OHRQoL<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Consecutively enrolled patients completed a survey including demographics, the Four\u2010Dimensional Six\n TMD<\/jats:styled-content>\n symptoms (\n 6Ts<\/jats:styled-content>\n \u2010\n 4D<\/jats:styled-content>\n ) screener,\n JFL<\/jats:styled-content>\n Scale\u20108 (\n JFLS<\/jats:styled-content>\n \u20108) and Oral Health Impact Profile for\n TMDs<\/jats:styled-content>\n (\n OHIP<\/jats:styled-content>\n \u2010\n TMD<\/jats:styled-content>\n ).\n TMD<\/jats:styled-content>\n diagnostic subtypes were subsequently determined according to the\n DC<\/jats:styled-content>\n \/\n TMD<\/jats:styled-content>\n protocol. Data were evaluated using chi\u2010square, non\u2010parametric tests and logistic regression (\n \u03b1<\/jats:italic>\n \u2009=\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 280 participants (mean age 31.2\u2009years [\n SD<\/jats:styled-content>\n 11.8]), 79.3% were female. Females showed significantly higher rates of combined pain\u2010related and intra\u2010articular\n TMDs<\/jats:styled-content>\n , more\n TMD<\/jats:styled-content>\n symptoms, more severe headaches, greater\n JFL<\/jats:styled-content>\n and poorer overall\n OHRQoL<\/jats:styled-content>\n than males. They also demonstrated stronger correlations between global\n TMD<\/jats:styled-content>\n severity and\n OHRQoL<\/jats:styled-content>\n dimensions (\n r<\/jats:italic>\n s\u2009=\u20090.38\u20130.66), as well as between\n JFL<\/jats:styled-content>\n and\n OHRQoL<\/jats:styled-content>\n (\n r<\/jats:italic>\n s\u2009=\u20090.48\u20130.79). Multivariate analysis revealed that high\n JFL<\/jats:styled-content>\n was significantly associated with jaw muscle pain (\n OR<\/jats:styled-content>\n 1.22), jaw joint pain (\n OR<\/jats:styled-content>\n 1.21),\n TMJ<\/jats:styled-content>\n closed\u2010lock (\n OR<\/jats:styled-content>\n 1.24) and open\u2010lock (\n OR<\/jats:styled-content>\n 1.25), while low\n OHRQoL<\/jats:styled-content>\n was related to jaw muscle pain (\n OR<\/jats:styled-content>\n 1.16), jaw joint pain (\n OR<\/jats:styled-content>\n 1.24), headache (\n OR<\/jats:styled-content>\n 1.23) and\n TMJ<\/jats:styled-content>\n closed\u2010lock (\n OR<\/jats:styled-content>\n 1.13).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Findings support sex\u2010informed\n TMD<\/jats:styled-content>\n care, though generalizability is constrained by study design and sample composition.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/joor.70103","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T06:35:04Z","timestamp":1763188504000},"page":"537-548","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Sex\u2010Related Differences in Temporomandibular Disorder Symptom Severity: Correlates With Jaw Function and Oral Health\u2010Related Quality of Life Among Patients"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0361-6209","authenticated-orcid":false,"given":"Adrian Ujin","family":"Yap","sequence":"first","affiliation":[{"name":"Centre for TMD & Orofacial Pain, Peking University School & Hospital of Stomatology Beijing China"},{"name":"Division of Dentistry, Ng Teng Fong General Hospital and Faculty of Dentistry, National University Health System Singapore"},{"name":"National Dental Research Institute Singapore, National Dental Centre Singapore and Duke\u2010NUS Medical School, Singapore Health Services Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3429-4436","authenticated-orcid":false,"given":"Jie","family":"Lei","sequence":"additional","affiliation":[{"name":"Centre for TMD & Orofacial Pain, Peking University School & Hospital of Stomatology Beijing China"},{"name":"Department of Oral & Maxillofacial Radiology, Peking University School & Hospital of Stomatology Beijing China"},{"name":"National Clinical Research Center for Oral Diseases Beijing China"},{"name":"National Engineering Laboratory for Digital and Material Technology of Stomatology Beijing China"},{"name":"Beijing Key Laboratory of Digital Stomatology Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4685-0399","authenticated-orcid":false,"given":"Cheng\u2010Ge","family":"Liu","sequence":"additional","affiliation":[{"name":"Centre for TMD & Orofacial Pain, Peking University School & Hospital of Stomatology Beijing China"},{"name":"Department of Oral & Maxillofacial Radiology, Peking University School & Hospital of Stomatology Beijing China"},{"name":"National Clinical Research Center for Oral Diseases Beijing China"},{"name":"National Engineering Laboratory for Digital and Material Technology of Stomatology Beijing China"},{"name":"Beijing Key Laboratory of Digital Stomatology Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5793-567X","authenticated-orcid":false,"given":"Zhi\u2010Wei","family":"Huang","sequence":"additional","affiliation":[{"name":"Centre for TMD & Orofacial Pain, Peking University School & Hospital of Stomatology Beijing China"},{"name":"Department of Oral & Maxillofacial Radiology, Peking University School & Hospital of Stomatology Beijing China"},{"name":"National Clinical Research Center for Oral Diseases Beijing China"},{"name":"National Engineering Laboratory for Digital and Material Technology of Stomatology Beijing China"},{"name":"Beijing Key Laboratory of Digital Stomatology Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7049-9888","authenticated-orcid":false,"given":"Kai Yuan","family":"Fu","sequence":"additional","affiliation":[{"name":"Centre for TMD & Orofacial Pain, Peking University School & Hospital of Stomatology Beijing China"},{"name":"Department of Oral & Maxillofacial Radiology, Peking University School & Hospital of Stomatology Beijing China"},{"name":"National Clinical Research Center for Oral Diseases Beijing China"},{"name":"National Engineering Laboratory for Digital and Material Technology of Stomatology Beijing China"},{"name":"Beijing Key Laboratory of Digital Stomatology Beijing 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