{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:20:06Z","timestamp":1790565606154,"version":"4.1.0"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The World Health Organization (WHO) defined intrinsic capacity (IC) as the combination of physical and mental resources essential for healthy aging. Currently, the role of oral health in relation to IC remains underexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine the associations among the number of remaining teeth and IC domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From the 30\u2009468 subjects of the National Health and Nutrition Examination Survey (NHANES) 2009\u20132014, we included 787 participants aged \u2265\u200960\u2009years with available dental\/IC\u2010related data, representing a weighted population of approximately 8.35 million U.S. older adults. Dentition status was categorised into four groups: \u2265\u200920 teeth, 10\u201319 teeth, 1\u20139 teeth and edentulous. IC domains (locomotion, vitality, psychological well\u2010being, sensory function and cognition) were operationalised using NHANES items aligned with WHO definitions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with participants with \u2265\u200920 teeth, those with 10\u201319 teeth had significantly higher odds of locomotion difficulty [adjusted\u2010odds ratio (OR): 2.18; 95% confidence interval (CI): 1.30\u20133.66], participants with 1\u20139 teeth\/edentulous also showed an increased risk of locomotion difficulty. The number of remaining teeth was also associated with reduced vitality, particularly unintentional weight loss and lower appetite. Edentulous participants had an increased risk of poor psychological well\u2010being, including depressive symptoms (adjusted\u2010OR: 1.91; 95% CI: 1.22\u20133.01) and anhedonia (adjusted\u2010OR: 2.27; 95% CI: 1.22\u20134.24). Significant associations were also found between edentulism and sensory impairments, particularly hearing loss (adjusted\u2010OR: 2.42; 95% CI: 1.17\u20134.99).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The number of remaining teeth in older adults was significantly associated with impairments across multiple IC domains. In particular, reduced dentition (10\u201319 teeth, 1\u20139 teeth or edentulism) was consistently linked to impaired locomotion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70138","type":"journal-article","created":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T07:34:45Z","timestamp":1766216085000},"page":"821-832","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Tooth Loss as a Risk Factor of Declining Intrinsic Capacity Domains in Later Life: Evidence From\n                    <scp>NHANES<\/scp>\n                    2009\u20132014"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9880-0481","authenticated-orcid":false,"given":"Vittorio","family":"Dibello","sequence":"first","affiliation":[{"name":"Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam [ACTA] University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"},{"name":"\u201cCesare Frugoni\u201d Internal and Geriatric Medicine and Memory Unit University of Bari \u201cAldo Moro\u201d  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5576-0432","authenticated-orcid":false,"given":"Karl G. H.","family":"Parisius","sequence":"additional","affiliation":[{"name":"Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam [ACTA] University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Lobbezoo","sequence":"additional","affiliation":[{"name":"Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam [ACTA] University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"},{"name":"Faculty of Odontology, Department of Orofacial Pain and Jaw Function Malm\u00f6 University  Malm\u00f6 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvano","family":"Quarto","sequence":"additional","affiliation":[{"name":"\u201cCesare Frugoni\u201d Internal and Geriatric Medicine and Memory Unit University of Bari \u201cAldo Moro\u201d  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Campus Biomedico University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madia","family":"Lozupone","sequence":"additional","affiliation":[{"name":"Department of Translational Biomedicine and Neuroscience \u2018DiBrain\u2019 University of Bari Aldo Moro  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Pace","sequence":"additional","affiliation":[{"name":"\u201cCesare Frugoni\u201d Internal and Geriatric Medicine and Memory Unit University of Bari \u201cAldo Moro\u201d  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Daniele","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Catholic University of Sacred Heart  Rome Italy"},{"name":"Neurology Unit, IRCCS Fondazione Policlinico Universitario A. 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