{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T12:29:06Z","timestamp":1790166546912,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Frailty reflects an age\u2010associated progressive decline in physiological reserve, increasing vulnerability to adverse outcomes. Burning Mouth Syndrome (BMS) is a chronic idiopathic orofacial pain disorder commonly seen in older individuals, yet its relationship with frailty remains uninvestigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      This study aims to assess frailty in BMS patients using the\n                      <jats:italic>SUNFRAIL+<\/jats:italic>\n                      multidimensional screening tool, which facilitates early detection of bio\u2010psycho\u2010social risk factors for frailty in community\u2010dwelling older adults.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This multi\u2010centre case\u2013control study included 104 adults aged \u2265\u200965\u2009years (52 with BMS and 52 age and sex matched controls). The\n                      <jats:italic>SUNFRAIL+<\/jats:italic>\n                      tool was used to identify risks and trigger further single\u2010domain evaluation with the Tool for Adherence to Therapies (TAS), Mini\u2010Nutritional Assessment (MNA), Mediterranean Diet Adherence Screener (PREDIMED), Short Physical Performance Battery (SPPB), Timed Up and Go test (TUG), Quick Mild Cognitive Impairment (Q\n                      <jats:italic>mci<\/jats:italic>\n                      ) screen, General Practitioner Assessment of Cognition (GPCOG), Geriatric Depression Scale (GDS), Social Provisions Scale (SPS), socio\u2010economic conditions self\u2010assessment questionnaire (MUSE) and 12\u2010item Short Form Health Survey (SF\u201012).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients with BMS showed significantly higher levels of frailty, characterized by higher rates of polypharmacy (76.9% vs. 30.8%), reduced mobility (61.5% vs. 42.3%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05), greater cognitive impairment (Q\n                      <jats:italic>mci<\/jats:italic>\n                      56.8 vs. 75.5), more self\u2010reported depressive symptoms (GDS: 7.5 vs. 4), less social support (SPS: 30 vs. 36), and lower quality of life (SF\u201012;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Older adults with BMS have a greater proportion of clinical markers of frailty. The\n                      <jats:italic>SUNFRAIL+<\/jats:italic>\n                      model is effective in revealing hidden vulnerabilities, supporting early, multidisciplinary intervention in this cohort.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70191","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:00:12Z","timestamp":1774519212000},"page":"1347-1362","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Uncovering Frailty in Burning Mouth Syndrome: Insights From a\n                    <scp>SUNFRAIL<\/scp>\n                    + Based Multidimensional Assessment"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4610-6690","authenticated-orcid":false,"given":"Federica","family":"Canfora","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Reproductive Sciences and Odontostomatology University of Naples \u201cFederico II\u201d  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3427-0514","authenticated-orcid":false,"given":"Giulia","family":"Ottaviani","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5284-5115","authenticated-orcid":false,"given":"Antonietta","family":"Argiuolo","sequence":"additional","affiliation":[{"name":"Departmental Program of Clinical Psychopathology Federico II University Hospital  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Giorgiutti","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8997-835X","authenticated-orcid":false,"given":"Guido","family":"Iaccarino","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6150-9439","authenticated-orcid":false,"given":"Katia","family":"Rupel","sequence":"additional","affiliation":[{"name":"Department of Surgical, Medical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Saccomanno","sequence":"additional","affiliation":[{"name":"Department of Life Science, Health, and Health Professions Link Campus University  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"De Luca","sequence":"additional","affiliation":[{"name":"Department of Public Health Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4619-0711","authenticated-orcid":false,"given":"Michele","family":"Virgolesi","sequence":"additional","affiliation":[{"name":"Department of Public Health Federico II University of Naples  Naples Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Moloney","sequence":"additional","affiliation":[{"name":"Health Service Executive of Ireland, National Oral Care Guideline (Supporting Smiles) Development Group and Mercy University Hospital  Cork City Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f3n\u00e1n","family":"O'Caoimh","sequence":"additional","affiliation":[{"name":"Health Service Executive of Ireland, National Oral Care Guideline (Supporting Smiles) Development Group and Mercy University 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