{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:05:15Z","timestamp":1785247515279,"version":"3.55.0"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with temporomandibular disorders (TMD) often exhibit widespread hypersensitivity and comorbidities, suggesting nociplastic pain (NP) involvement. Aerobic exercise (AE) and strength training (ST) enhance tissue oxygenation, pain inhibition, and quality of life. This study compares AE and ST, combined with physical therapy (PT), on NP and TMD clinical features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This randomized\u2010controlled trial with blinded assessors assigned 43 TMD and NP patients to PT (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200915), PT\u2009+\u2009AE (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200915), or PT\u2009+\u2009ST (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200913). A 6\u2010week intervention included 12 PT sessions (education, manual therapy, jaw\/neck exercises), with PT\u2009+\u2009AE performing high\u2010intensity intervallic AE (stationary bike) and PT\u2009+\u2009ST upper\/lower extremities exercises. Primary outcome: pressure pain thresholds (PPT) with algometer. Secondary outcomes: central sensitization (CS)\u2010related symptoms, muscle strength, pain intensity, anxiety, sleep quality, kinesiophobia. Outcomes were assessed post\u2010intervention (T1) and at 12\u2010week follow\u2010up (T2).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At T1, PT\u2009+\u2009AE demonstrated significant reductions than PT in CS (\u22129.5;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), pain (\u221223.2;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), kinesiophobia (\u22124.1;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), sleep impairment (\u22123.8;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). Pain reductions persisted at T2 (VAS \u221226.2;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04). PT\u2009+\u2009ST reduced kinesiophobia only at T2 (\u22123.8;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). At T1, PT\u2009+\u2009AE improved proximal\u2010PPT against PT\u2009+\u2009ST (\u22120.52\u2009kg\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03), while PT\u2009+\u2009ST enhanced trapezius strength (10.9\u2009kg;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Adding AE or ST to PT improves outcomes in TMD patients and NP, with PT\u2009+\u2009AE reducing pain and CS\u2010related symptoms more effectively.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70278","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T13:16:16Z","timestamp":1785244576000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Aerobic Exercise and Strength Training on Nociplastic Pain and Clinical Features in Temporomandibular Disorders With Myalgia: A Randomized\u2010Controlled Trial"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9815-2374","authenticated-orcid":false,"given":"Flora","family":"Dantony","sequence":"first","affiliation":[{"name":"Department of Physiotherapy, Faculty of Medicine and Health Sciences Universitat Internacional de Catalunya  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Romero\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Faculty of Medicine and Health Sciences Universitat Internacional de Catalunya  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2961-9328","authenticated-orcid":false,"given":"David","family":"Blanco","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Faculty of Medicine and Health Sciences Universitat Internacional de Catalunya  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0206-6412","authenticated-orcid":false,"given":"Carlos Antonio","family":"Z\u00e1rate\u2010Tejero","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Faculty of Medicine and Health Sciences Universitat Internacional de Catalunya  Barcelona 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