{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T09:48:50Z","timestamp":1791625730288,"version":"4.3.4"},"reference-count":102,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evidence on how periodontitis affects oral function related to ingestion remains limited. Understanding these functional consequences is important for incorporating function\u2010focused care into periodontal practice and for improving oral health and quality of life. This review examined whether periodontal disease is associated with impairments of oral functions and whether periodontal therapy may improve these functions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Types of Studies Reviewed<\/jats:title>\n                    <jats:p>This systematic review followed PRISMA 2020 guidelines and was registered in PROSPERO (CRD42024619735). A systematic search of PubMed and Cochrane Library was conducted for studies published between January 2010 and December 2024. Of 4004 records screened, 47 met the inclusion criteria. The included studies comprised 28 cross\u2010sectional studies, 18 prospective clinical studies, and one longitudinal observational study. Risk of bias was assessed using RoB 2 for randomised controlled trials, ROBINS\u2010I for non\u2010randomised interventional studies, and ROBINS\u2010E for studies evaluating exposure effects. Data were synthesised using qualitative and quantitative approaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The oral functions assessed were salivary function, mastication, biting, and self\u2010reported oral functional outcomes. Most studies reported reduced salivary flow, bite force, and masticatory performance in individuals with periodontitis, while many prospective studies described functional improvement after periodontal therapy. Meta\u2010analyses showed that individuals with periodontitis had significantly lower salivary flow (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u2009\u22121.14,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and higher eating\u2010related disability scores (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u20090.45,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) than healthy controls. Periodontal therapy was associated with a significant increase in salivary flow (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u20090.41,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.043). An exploratory meta\u2010analysis also suggested a reduction in eating\u2010related disability after treatment (Hedges'\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u2009\u22120.34,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005), although this finding should be interpreted cautiously because the pooled studies included different interventional designs. Evidence regarding swallowing\u2010related outcomes was extremely limited, with only two studies assessing this domain and neither demonstrating a significant association with periodontal disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Practical Implications<\/jats:title>\n                    <jats:p>Periodontal disease appears to be associated with impaired oral function, particularly mastication, biting, salivary function, and chewing\u2010related quality\u2010of\u2010life outcomes. Periodontal therapy may contribute to partial functional improvement in some of these domains. Periodontal care should therefore consider not only disease control but also preservation and improvement of oral function. Future research should prioritise longitudinal and well\u2010designed interventional studies to clarify causal relationships and quantify functional recovery after periodontal therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70295","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:16:10Z","timestamp":1787796970000},"page":"2198-2222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["How Periodontal Disease Compromises Oral Functions Related to Ingestion: Evidence From Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3140-9631","authenticated-orcid":false,"given":"Thomas","family":"Douillard","sequence":"first","affiliation":[{"name":"UFR d'Odontologie, Clinical Odontology Research Center (CROC) University of Clermont Auvergne  Clermont\u2010Ferrand France"},{"name":"Odontology Department CHU Clermont\u2010Ferrand  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8173-2606","authenticated-orcid":false,"given":"Martine","family":"Hennequin","sequence":"additional","affiliation":[{"name":"UFR d'Odontologie, Clinical Odontology Research Center (CROC) University of Clermont Auvergne  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7022-469X","authenticated-orcid":false,"given":"Emmanuel","family":"Nicolas","sequence":"additional","affiliation":[{"name":"UFR d'Odontologie, Clinical Odontology Research Center (CROC) University of Clermont Auvergne  Clermont\u2010Ferrand France"},{"name":"Odontology Department CHU Clermont\u2010Ferrand  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0958-5143","authenticated-orcid":false,"given":"Nada","family":"El Osta","sequence":"additional","affiliation":[{"name":"UFR d'Odontologie, Clinical Odontology Research Center (CROC) University of Clermont Auvergne  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13769"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.709438"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1385436"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2013.05.012"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.appet.2024.107287"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1877\u20107864(25)78642\u20105"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00263"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753\u20104887.2010.00334.x"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.050355"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2006.060025"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2004.10.009"},{"issue":"2","key":"e_1_2_13_13_1","first-page":"147","article-title":"Periodontal Health and Its Relationship With Salivary Factors Among Different Age Groups in a Saudi Population","volume":"6","author":"Farsi N.","year":"2008","journal-title":"Oral Health & Preventive Dentistry"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2008.05.009"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807\u20103107BOR\u20102017.vol31.0008"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.54.151"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(25)00672\u20105"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/sja.SJA_543_18"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2024.108602"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.1260"},{"key":"e_1_2_13_24_1","volume-title":"Statistical Method for Meta\u2010Analysis","author":"Hedges L. 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