{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T09:48:45Z","timestamp":1791625725173,"version":"4.3.4"},"reference-count":50,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005283","name":"Funda\u00e7\u00e3o Cearense de Apoio ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["BMD\u20100008\u201002870.01.01\/23"],"award-info":[{"award-number":["BMD\u20100008\u201002870.01.01\/23"]}],"id":[{"id":"10.13039\/501100005283","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005283","name":"Funda\u00e7\u00e3o Cearense de Apoio ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["BMD\u20100008\u201002870.01.11\/25"],"award-info":[{"award-number":["BMD\u20100008\u201002870.01.11\/25"]}],"id":[{"id":"10.13039\/501100005283","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Conventional complete dentures (CDs) fabrication involves multiple clinical and laboratory steps. Simplified protocols reduce treatment burden. However, their impact on patient\u2010reported outcomes remains debated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This systematic review and meta\u2010analysis evaluated the oral health\u2010related quality of life (OHRQoL), patient satisfaction, and masticatory ability of CDs fabricated using simplified versus traditional protocols.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Seven databases were searched up to July 2026 for randomised controlled trials (RCTs) comparing simplified and conventional CDs fabrication protocols. Two reviewers independently assessed records and risk of bias using the Cochrane RoB 2 tool. Mean differences and 95% confidence intervals were meta\u2010analysed using random\u2010effects models. Heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      ), subgroup analyses according to follow\u2010up periods, small\u2010study effects\/funnel plot asymmetry using Egger's test when applicable, and evidence certainty using GRADE were assessed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty\u2010two RCTs were included. Simplified procedures were typically characterised by single\u2010stage impression procedures, absence of facebow records, and a single trial denture session. Most studies had some concerns or a high risk of bias. Meta\u2010analyses showed no statistically significant differences between protocols regarding OHRQoL (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.620;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090%), overall satisfaction (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.440;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20095%), and masticatory ability (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.610). Evidence of funnel plot asymmetry\/small\u2010study effect was detected only for patient satisfaction (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033). The certainty of the evidence was rated as moderate to very low across outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Greater procedural complexity in complete denture fabrication was not associated with superior OHRQoL, patient satisfaction, or masticatory ability. Within the certainty limits of the available evidence, simplified protocols may be a pragmatic alternative to conventional fabrication.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70301","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T06:08:05Z","timestamp":1788242885000},"page":"2223-2235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Do Simplified Complete Denture Protocols Preserve Patient\u2010Reported Outcomes? A Systematic Review and Meta\u2010Analysis of Randomised Controlled Trials"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9455-7410","authenticated-orcid":false,"given":"Isabelle da Costa Goes","family":"Timb\u00f3","sequence":"first","affiliation":[{"name":"Graduate Program in Dentistry, Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9073-652X","authenticated-orcid":false,"given":"Sarah Vit\u00f3ria Lutif de Lemos","family":"Moura","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2368-6735","authenticated-orcid":false,"given":"Yuri Barbosa","family":"de Azev\u00eado","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6261-1972","authenticated-orcid":false,"given":"Rayrah Kayane Santos","family":"Moreira","sequence":"additional","affiliation":[{"name":"Graduate Program in Dentistry, Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1513-9027","authenticated-orcid":false,"given":"Paulo Goberl\u00e2nio de Barros","family":"Silva","sequence":"additional","affiliation":[{"name":"Division of Oral Pathology, School of Dentistry Christus University  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2746-2219","authenticated-orcid":false,"given":"Livia Maria Sales Pinto","family":"Flamengui","sequence":"additional","affiliation":[{"name":"Graduate Program in Dentistry, Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing Federal University of Cear\u00e1  Fortaleza Cear\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6845-0767","authenticated-orcid":false,"given":"Raniel Fernandes","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Graduate Program in Dentistry, Department of Restorative Dentistry, Faculty of Pharmacy, Dentistry and Nursing Federal University of Cear\u00e1  Fortaleza Cear\u00e1 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