{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:05:36Z","timestamp":1790129136783,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Adults with intellectual disabilities often experience tooth loss and face barriers to accessing implant\u2010supported rehabilitation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate implant\u2010supported prosthesis outcomes in adults with non\u2010syndromic intellectual disabilities and to identify variables associated with prosthetic success.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 247 implant\u2010supported prostheses placed in 137 patients from 7 dental centers in Spain, France, Italy, and South Korea were analysed. Patient characteristics, oral health, implant features, and prosthesis\u2010related variables were collected. Prosthetic outcomes were categorized as \u201cundamaged and successful\u201d, \u201cdamaged but successful\u201d, \u201closs\u201d, or \u201cundamaged but unsuccessful\u201d. Success was assessed using an adapted United States Public Health Service (USPHS) clinical rating system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At a mean follow\u2010up of 68.1\u2009months, 94.3% of prostheses were considered successful. Cumulative survival rates were 97% at 5\u2009years, 88% at 10\u2009years, and 85% at 15\u2009years. The most common technical complications were screw loosening (10.4%) and chipping (10%). Fixed prostheses predominated (92.3%), with 65.3% crowns and 34.6% bridges. Screw retention was most common (84.2%), and 94.3% followed a conventional loading protocol. General anaesthesia was used in nearly half of the cases during the impression step, although most framework and delivery procedures were performed without sedation. Among the multinomial mixed\u2010effects models, implant design was significantly associated with the outcome category \u201cdamaged but successful\u201d, whereas age at first implant surgery was significantly associated with the outcome category \u201closs\u201d (OR\u2009=\u20090.93 per additional year; 95% CI: 0.87\u20130.99;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031). However, the model showed no overall discriminatory ability (AUC\u2010ROC\u2009=\u20090.500), and these associations should therefore be considered exploratory rather than clinically predictive. Random\u2010effects binomial models showed improved discrimination (AUC\u2010ROC\u2009=\u20090.754), although no statistically significant associations were identified.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Implant\u2010supported prosthetic rehabilitation is a viable and successful long\u2010term treatment option for adults with non\u2010syndromic intellectual disabilities, achieving outcomes comparable to those in the general population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70315","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:50:52Z","timestamp":1790128252000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dental Implants in Adults With Intellectual Disabilities: A Multicenter Retrospective Study. Part 2: Prosthesis Outcomes"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3425-9489","authenticated-orcid":false,"given":"Javier","family":"Fern\u00e1ndez\u2010Feijoo","sequence":"first","affiliation":[{"name":"University of Santiago de Compostela and Health Research Institute of Santiago de Compostela  Santiago Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Bratos\u2010Bobo","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Dental Bratos  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Bratos\u2010Morillo","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Dental Bratos  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1191-5658","authenticated-orcid":false,"given":"Denise","family":"Faulks","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CROC, and CHU Clermont\u2010Ferrand, Service D'odontologie  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9888-5884","authenticated-orcid":false,"given":"Marie\u2010Sophie","family":"Bogner","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CROC, and CHU Clermont\u2010Ferrand, Service D'odontologie  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Derchu","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CROC, and CHU Clermont\u2010Ferrand, Service D'odontologie  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Eschevins","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CROC, and CHU Clermont\u2010Ferrand, Service D'odontologie  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7022-469X","authenticated-orcid":false,"given":"Emmanuel","family":"Nicolas","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CROC, and CHU Clermont\u2010Ferrand, Service D'odontologie  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre Yves","family":"Cousson","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CROC, and CHU Clermont\u2010Ferrand, Service D'odontologie  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Auduc","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Clermont Auvergne, CROC, and CHU Clermont\u2010Ferrand, Service D'odontologie  Clermont\u2010Ferrand France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5171-6426","authenticated-orcid":false,"given":"Yoo","family":"Soo\u2010Yeon","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Dental Research Institute, Seoul National University Dental Hospital, School of Dentistry Seoul National University  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1483-401X","authenticated-orcid":false,"given":"Pedro","family":"Diz\u2010Dios","sequence":"additional","affiliation":[{"name":"University of Santiago de Compostela and Health Research Institute of Santiago de Compostela  Santiago Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Gasam\u00e1ns\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"University of Santiago de Compostela and Health Research Institute of Santiago de Compostela  Santiago Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6340-1993","authenticated-orcid":false,"given":"Jacobo","family":"Limeres\u2010Posse","sequence":"additional","affiliation":[{"name":"University of Santiago de Compostela and Health Research Institute of Santiago de Compostela  Santiago Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8894-3796","authenticated-orcid":false,"given":"P.","family":"Paolo Appendino","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliera Mauriziano di Torino  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6751-4397","authenticated-orcid":false,"given":"Simone","family":"Buttiglieri","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliera Mauriziano di Torino  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7825-6132","authenticated-orcid":false,"given":"F.","family":"Francesco Della Ferrera","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliera Mauriziano di Torino  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Rozza","sequence":"additional","affiliation":[{"name":"University Hospital Santi Paolo e Carlo University of Milan  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2201-8485","authenticated-orcid":false,"given":"Fabio","family":"Brusamolino","sequence":"additional","affiliation":[{"name":"Azienda Socio Sanitaria Territoriale Dei Sette Laghi  Varese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5349-1091","authenticated-orcid":false,"given":"M\u00e1rcio","family":"Diniz\u2010Freitas","sequence":"additional","affiliation":[{"name":"University of Santiago de Compostela and Health Research Institute of Santiago de Compostela  Santiago Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.prosdent.2023.09.013","article-title":"Implant\u2010Supported Prostheses in Patients With Special Needs: A Systematic Literature Review of Protocols and Outcomes","volume":"134","author":"Bogner M.","year":"2025","journal-title":"Journal of Prosthetic Dentistry"},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1046\/j.1365-2842.2002.00890.x","article-title":"Consequences of Oral Rehabilitation on Dyskinesia in Adults With Down's Syndrome: A Clinical Report","volume":"29","author":"Faulks D.","year":"2002","journal-title":"Journal of Oral Rehabilitation"},{"key":"e_1_2_11_4_1","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.tripleo.2009.06.027","article-title":"Oral Microbial and Respiratory Status of Persons With Mental Retardation\/Intellectual and Developmental Disability: An Observational Cohort Study","volume":"108","author":"Binkley C. J.","year":"2009","journal-title":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},{"key":"e_1_2_11_5_1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jpor.2016.04.005","article-title":"Why Do Edentulous Adults With Intellectual Disabilities Not Wear Dentures? Wave 2 of the IDS TILDA Cohort Study","volume":"61","author":"Mac GiollaPhadraig C.","year":"2017","journal-title":"Journal of Prosthodontic Research"},{"key":"e_1_2_11_6_1","doi-asserted-by":"crossref","first-page":"562","DOI":"10.11607\/jomi.9880","article-title":"Could Fixed Implants Be a Viable Treatment Option in Disabled Patients? A Clinical Retrospective Study","volume":"38","author":"Yoo S.","year":"2023","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_11_7_1","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.3109\/09638288.2012.667189","article-title":"Osseointegrated Dental Implants in Patients With Intellectual Disability: A Pilot Study","volume":"34","author":"Feijoo J. F.","year":"2012","journal-title":"Disability and Rehabilitation"},{"key":"e_1_2_11_8_1","doi-asserted-by":"crossref","first-page":"517","DOI":"10.11607\/ijp.3511","article-title":"Treatment With Implant\u2010Supported Fixed Dental Prostheses in Patients With Congenital and Acquired Neurologic Disabilities: A Prospective Study","volume":"26","author":"Ekfeldt A.","year":"2013","journal-title":"International Journal of Prosthodontics"},{"issue":"16","key":"e_1_2_11_9_1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/clr.13298","article-title":"Group 2 ITI Consensus Report: Prosthodontics and Implant Dentistry","volume":"29","author":"Morton D.","year":"2018","journal-title":"Clinical Oral Implants Research"},{"key":"e_1_2_11_10_1","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00784-005-0018-z","article-title":"Reprint of Criteria for the Clinical Evaluation of Dental Restorative Materials. 1971","volume":"9","author":"Cvar J. F.","year":"2005","journal-title":"Clinical Oral Investigations"},{"issue":"3","key":"e_1_2_11_11_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1600-0501.2007.01439.x","article-title":"Comparison of Survival and Complication Rates of Tooth\u2010Supported Fixed Dental Prostheses (FDPs) and Implant\u2010Supported FDPs and Single Crowns (SCs)","volume":"18","author":"Pjetursson B. E.","year":"2007","journal-title":"Clinical Oral Implants Research"},{"issue":"6","key":"e_1_2_11_12_1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1600-0501.2012.02546.x","article-title":"A Systematic Review of the Survival and Complication Rates of Implant\u2010Supported Fixed Dental Prostheses (FDPs) After a Mean Observation Period of at Least 5\u2009Years","volume":"23","author":"Pjetursson B. E.","year":"2012","journal-title":"Clinical Oral Implants Research"},{"key":"e_1_2_11_13_1","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1902\/jop.2009.090109","article-title":"Descriptive Analysis of Implant and Prosthodontic Survival Rates With Fixed Implant\u2010Supported Rehabilitations in the Edentulous Maxilla","volume":"80","author":"Lambert F. E.","year":"2009","journal-title":"Journal of Periodontology"},{"key":"e_1_2_11_14_1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.1754-4505.2006.tb01509.x","article-title":"Dental Implants in Edentulous Adults With Cognitive Disabilities: Report of a Pilot Project","volume":"26","author":"Durham T. M.","year":"2006","journal-title":"Special Care in Dentistry"},{"key":"e_1_2_11_15_1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1922\/EJPRD_2765Sharma09","article-title":"Evaluating the Long\u2010Term Success of Removable and Fixed Prosthodontic Treatment in Completely Edentulous Patients: Comparative Clinical\u2010 Radiographic Study","volume":"33","author":"Sharma A.","year":"2025","journal-title":"European Journal of Prosthodontics and Restorative Dentistry"},{"key":"e_1_2_11_16_1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/prd.12416","article-title":"Prosthetic Failures in Dental Implant Therapy","volume":"88","author":"Sailer I.","year":"2022","journal-title":"Periodontology 2000"},{"key":"e_1_2_11_17_1","first-page":"534","article-title":"Dental Implants in Persons With Severe Epilepsy and Multiple Disabilities: A Long\u2010Term Retrospective Study","volume":"24","author":"Cune M. S.","year":"2009","journal-title":"International Journal of Oral and Maxillofacial Implants"},{"key":"e_1_2_11_18_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2025.105738","article-title":"Bruxism and Direct and Indirect Restorations Failure: A Scoping Review","volume":"157","author":"Al\u2010Talib T.","year":"2025","journal-title":"Journal of Dentistry"},{"key":"e_1_2_11_19_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/scd.12677","article-title":"Dental Treatment Under Intravenous Sedation Prolongs Longevity of a Fixed Prosthesis in Patients With Intellectual Disabilities","volume":"42","author":"Yamaguchi\u2010Komeyama K.","year":"2022","journal-title":"Special Care in Dentistry"},{"key":"e_1_2_11_20_1","first-page":"579","article-title":"The Influence of Gender and Age on Fixed Prosthetic Restoration Longevity: An up to 18\u2010 to 20\u2010Year Follow\u2010Up in an Undergraduate Clinic","volume":"20","author":"De Backer H.","year":"2007","journal-title":"International Journal of Prosthodontics"},{"key":"e_1_2_11_21_1","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1016\/j.prosdent.2024.08.019","article-title":"Is the Clinical Performance of Dental Implants Influenced by Different Macrogeometries? A Systematic Review and Meta\u2010Analysis","volume":"134","author":"Reis\u2010Neta G. R. D.","year":"2025","journal-title":"Journal of Prosthetic Dentistry"},{"key":"e_1_2_11_22_1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41432-025-01202-y","article-title":"Do Tapered Implants Offer Clinical Advantages Over Cylindrical Implants in Early Healing?","volume":"27","author":"Mour\u00e3o C. F.","year":"2026","journal-title":"Evidence\u2010Based Dentistry"},{"issue":"26","key":"e_1_2_11_23_1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/jcpe.13823","article-title":"Prevention and Treatment of Peri\u2010Implant Diseases\u2500the EFP S3 Level Clinical Practice Guideline","volume":"50","author":"Herrera D.","year":"2023","journal-title":"Journal of Clinical Periodontology"},{"key":"e_1_2_11_24_1","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1111\/joor.13683","article-title":"Dental Implant Considerations in Patients With Systemic Diseases: An Updated Comprehensive Review","volume":"51","author":"Mosaddad S. A.","year":"2024","journal-title":"Journal of Oral Rehabilitation"},{"key":"e_1_2_11_25_1","doi-asserted-by":"crossref","first-page":"e478","DOI":"10.4317\/medoral.19564","article-title":"Implants in Disabled Patients: A Review and Update","volume":"19","author":"Romero\u2010P\u00e9rez M.","year":"2014","journal-title":"Medicina Oral, Patologia Oral, Cirugia Bucal"},{"key":"e_1_2_11_26_1","first-page":"288","article-title":"Implants in Handicapped Patients","volume":"8","author":"L\u00f3pez\u2010Jim\u00e9nez J.","year":"2003","journal-title":"Medicina Oral"},{"key":"e_1_2_11_27_1","first-page":"132","article-title":"Early Experience of Implant\u2010Supported Prostheses in Patients With Neurologic Disabilities","volume":"18","author":"Ekfeldt A.","year":"2005","journal-title":"International Journal of Prosthodontics"},{"key":"e_1_2_11_28_1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.17245\/jdapm.2017.17.3.205","article-title":"Prognosis Following Dental Implant Treatment Under General Anesthesia in Patients With Special Needs","volume":"17","author":"Kim I.","year":"2017","journal-title":"Journal of Dental Anesthesia and Pain Medicine"},{"key":"e_1_2_11_29_1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.ridd.2010.12.018","article-title":"Prevalence of Intellectual Disability: A Meta\u2010Analysis of Population\u2010Based Studies","volume":"32","author":"Maulik P. K.","year":"2011","journal-title":"Research in Developmental Disabilities"},{"issue":"25","key":"e_1_2_11_30_1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/clr.14074","article-title":"Relevant Domains, Core Outcome Sets and Measurements for Implant Dentistry Clinical Trials: The Implant Dentistry Core Outcome Set and Measurement (ID\u2010COSM) International Consensus Report","volume":"34","author":"Tonetti M. S.","year":"2023","journal-title":"Clinical Oral Implants Research"},{"issue":"26","key":"e_1_2_11_31_1","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/clr.14068","article-title":"Oral Function in Completely Edentulous Patients Rehabilitated With Implant\u2010Supported Dental Prostheses: A Systematic Review and Meta\u2010Analysis","volume":"34","author":"Srinivasan M.","year":"2023","journal-title":"Clinical Oral Implants Research"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.70315","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/joor.70315","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/joor.70315","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:50:57Z","timestamp":1790128257000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/joor.70315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,22]]},"references-count":30,"alternative-id":["10.1111\/joor.70315"],"URL":"https:\/\/doi.org\/10.1111\/joor.70315","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,22]]},"assertion":[{"value":"2025-11-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"joor.70315"}}