{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T08:37:09Z","timestamp":1792831029737,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:00:00Z","timestamp":1792800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:00:00Z","timestamp":1792800000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Oral Rehabilitation"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Recent studies suggested that Temporomandibular joint disorder (TMD) may be more prevalent in patients with Parkinson's disease (PD), but lack international standardized clinical assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to investigate the correlation between the Diagnostic Criteria for TMD (DC\/TMD) diagnosis and PD motor symptoms, and to investigate the presence of TMD in PD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>419 participants from the outpatient clinic of the Department of Neurology were enrolled. Patient's TMD status was diagnosed with DC\/TMD. PD motor symptoms and severity were assessed by the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS\u2010UPDRS) part III and Modified Hoehn and Yahr scale (HY).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      45.6% of PD participants were diagnosed with TMD, with Anterior Disc Displacement with Reduction being the most common TMD subtype (27.4%), followed by Degenerative Joint Disease (6.9%). Compared to PD patients without TMD, those with TMD exhibited more advanced motor dysfunction (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.043). Occurrence of Pain\u2010related TMD was correlated with bradykinesia (rho\u2009=\u20090.135,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) and axial symptoms (rho\u2009=\u20090.125,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010), while Intra\u2010articular joint disorder was correlated with tremor (rho\u2009=\u20090.097,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.047). PD patients with longer disease duration were associated with higher odds of TMD diagnosis (OR\u2009=\u20091.064,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TMD subtypes are associated with specific motor manifestations in PD: pain\u2010related TMD correlated with bradykinesia and axial impairment, whereas intra\u2010articular joint disorders correlated with tremor. Multidisciplinary collaboration between dentists and neurologists is essential and may benefit the management for both PD and TMD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/joor.70352","type":"journal-article","created":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T07:54:48Z","timestamp":1792828488000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporomandibular Joint Disorder in Parkinson's Disease Patients"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6848-9215","authenticated-orcid":false,"given":"Ziyu","family":"Ge","sequence":"first","affiliation":[{"name":"Department of General Dentistry The Second Affiliated Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4140-109X","authenticated-orcid":false,"given":"Jing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Stomatology Hangzhou Hospital of Traditional Chinese Medicine  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9940-9327","authenticated-orcid":false,"given":"Xinhui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology The Second Affiliated Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5693-2060","authenticated-orcid":false,"given":"Rundong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of General Dentistry The Second Affiliated Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7890-6281","authenticated-orcid":false,"given":"Yanzhen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of General Dentistry The Second Affiliated Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6951-7698","authenticated-orcid":false,"given":"Wei","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Neurology The Second Affiliated Hospital Zhejiang University School of Medicine  Hangzhou Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,24]]},"reference":[{"issue":"5","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1056\/NEJMra2401857","article-title":"Parkinson's Disease","volume":"391","author":"Tanner C. 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S.","year":"2023","journal-title":"Diagnostics"},{"issue":"9","key":"e_1_2_12_8_1","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1111\/joor.13496","article-title":"Prevalence of Temporomandibular Disorders in Subjects Affected by Parkinson Disease: A Systematic Review and Metanalysis","volume":"50","author":"Minervini G.","year":"2023","journal-title":"Journal of Oral Rehabilitation"},{"issue":"6","key":"e_1_2_12_9_1","doi-asserted-by":"crossref","first-page":"747","DOI":"10.3390\/brainsci11060747","article-title":"Association Between Temporomandibular Joint Disorder and Parkinson's Disease","volume":"11","author":"Choi H.\u2010G.","year":"2021","journal-title":"Brain Sciences"},{"issue":"1","key":"e_1_2_12_10_1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1186\/s12903-023-03051-6","article-title":"Orofacial Function and Temporomandibular Disorders in Parkinson's Disease: A Case\u2010Controlled Study","volume":"23","author":"Baram S.","year":"2023","journal-title":"BMC Oral Health"},{"issue":"1","key":"e_1_2_12_11_1","doi-asserted-by":"crossref","DOI":"10.1097\/PR9.0000000000000923","article-title":"Orofacial Pain in 1916 Patients With Early or Moderate Parkinson Disease","volume":"6","author":"O'Neill F.","year":"2021","journal-title":"Pain Reports"},{"issue":"4","key":"e_1_2_12_12_1","first-page":"268","article-title":"\u4e2d\u56fd\u5e15\u91d1\u68ee\u75c5\u7684\u8bca\u65ad\u6807\u51c6","volume":"49","author":"\u5218\u519b","year":"2016","journal-title":"Zhonghua Shen Jing Ke Za Zhi"},{"issue":"3","key":"e_1_2_12_13_1","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1589\/jpts.27.887","article-title":"Impact in Oral Health and the Prevalence of Temporomandibular Disorder in Individuals With Parkinson's Disease","volume":"27","author":"Costa Silva P. 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M. D.","year":"2019","journal-title":"Revista CEFAC"},{"issue":"9","key":"e_1_2_12_19_1","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1111\/joor.12661","article-title":"Gender Differences in Temporomandibular Disorders in Adult Populational Studies: A Systematic Review and Meta\u2010Analysis","volume":"45","author":"Bueno C.","year":"2018","journal-title":"Journal of Oral Rehabilitation"},{"issue":"6","key":"e_1_2_12_20_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0217763","article-title":"The Association Between Parkinson's Disease and Temporomandibular Disorder","volume":"14","author":"Chen Y.\u2010Y.","year":"2019","journal-title":"PLoS One"},{"issue":"4","key":"e_1_2_12_21_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.12871\/00039829202041","article-title":"Does Parkinson's Disease Interfere With Electromyographic Fatigue of Masticatory Muscles?","volume":"157","author":"Palinkas M.","year":"2019","journal-title":"Archives Italiennes de Biologie"},{"issue":"6","key":"e_1_2_12_22_1","doi-asserted-by":"crossref","first-page":"839","DOI":"10.5664\/jcsm.5882","article-title":"Does Postural Rigidity Decrease During REM Sleep Without Atonia in Parkinson Disease?","volume":"12","author":"Arnaldi D.","year":"2016","journal-title":"Journal of Clinical Sleep Medicine"},{"key":"e_1_2_12_23_1","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1007\/s00784-020-03566-0","article-title":"Is Dopaminergic Medication Dose Associated With Self\u2010Reported Bruxism in Parkinson's Disease? 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A Systematic Review","volume":"40","author":"Rocha C.","year":"2013","journal-title":"Journal of Oral Rehabilitation"},{"issue":"1","key":"e_1_2_12_33_1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1097\/NPT.0000000000000160","article-title":"Exploring the Effects of Using an Oral Appliance to Reduce Movement Dysfunction in an Individual With Parkinson Disease: A Single\u2010Subject Design Study","volume":"41","author":"Lane H.","year":"2017","journal-title":"Journal of Neurologic Physical Therapy"},{"issue":"3","key":"e_1_2_12_34_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1080\/08990220.2021.1953462","article-title":"Pilot Trial of a Mouthpiece as Treatment for Signs and Symptoms of Parkinson Disease","volume":"38","author":"May D. 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