{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T13:47:04Z","timestamp":1762955224257},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,8,19]],"date-time":"2013-08-19T00:00:00Z","timestamp":1376870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Dicle University Scientific Research Projects Coordination Office"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The biostimulation effects of low\u2010level laser therapy (<jats:styled-content style=\"fixed-case\">LLLT<\/jats:styled-content>) have been demonstrated recently. This study investigated the effects of <jats:styled-content style=\"fixed-case\">LLLT<\/jats:styled-content> on palatal mucoperiosteal wound healing and oxidative stress status in rats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and method<\/jats:title><jats:p>Forty\u2010two male Wistar rats weighing 250\u2013300\u00a0g were used in this study. A standardized full\u2010thickness wound was created in the mucoperiosteum of the hard palates of the rats using a 3\u2010mm\u2010diameter biopsy punch. Treatment using a GaAlAs laser at a wavelength of 940\u00a0nm and a dose of 10\u00a0J\/cm<jats:sup>2<\/jats:sup> was initiated after surgery and repeated on the 2nd, 4th, and 6th days post\u2010surgery. Seven animals from each group were sacrificed on the 7th, 14th, and 21st days after surgery. Total antioxidant status and total oxidative status were measured in serum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The histopathological findings revealed reduced numbers of inflammatory cells on the 7th day, increased mitotic activity of fibroblasts on the 14th and 21st day, and the same degree of collagen synthesis and vascularization on the days 7, 14, and 21 in the <jats:styled-content style=\"fixed-case\">LLLT<\/jats:styled-content> group compared with the control group. No significant differences in total oxidative status and total antioxidant status were observed between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">LLLT<\/jats:styled-content> using a GaAlAs laser at a wavelength of 940\u00a0nm and a dose of 10\u00a0J\/cm<jats:sup>2<\/jats:sup> elicited a positive healing effect on palatal mucoperiosteal wounds likely via the induction of fibroblasts. The oxidative stress status was not affected by <jats:styled-content style=\"fixed-case\">LLLT<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jop.12106","type":"journal-article","created":{"date-parts":[[2013,8,19]],"date-time":"2013-08-19T06:28:34Z","timestamp":1376893714000},"page":"103-110","source":"Crossref","is-referenced-by-count":22,"title":["The effect of low\u2010level laser therapy on the healing of hard palate mucosa and the oxidative stress status of rats"],"prefix":"10.1111","volume":"43","author":[{"given":"Ela Tules","family":"Firat","sequence":"first","affiliation":[{"name":"Department of Periodontology Faculty of Dentistry Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Da\u011f","sequence":"additional","affiliation":[{"name":"Department of Periodontology Faculty of Dentistry Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"G\u00fcnay","sequence":"additional","affiliation":[{"name":"Department of Periodontology Faculty of Dentistry Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beyza","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Faculty of Dentistry Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet \u0130rfan","family":"Karadede","sequence":"additional","affiliation":[{"name":"Department of Orthodontics Faculty of Dentistry Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berna","family":"Ers\u00f6z Kanay","sequence":"additional","affiliation":[{"name":"Department of Surgery Faculty of Veterinary Medicine Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayd\u0131n","family":"Ketani","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology Faculty of Veterinary Medicine Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osman","family":"Evliyao\u011flu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Faculty of Medicine Dicle University Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ersin","family":"Uysal","sequence":"additional","affiliation":[{"name":"Department of Computer Tech. 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