{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:09:58Z","timestamp":1791389398470,"version":"4.3.3"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,8,10]],"date-time":"2013-08-10T00:00:00Z","timestamp":1376092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Moebius syndrome (<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content>) is a rare congenital condition that is characterised by facial hypomimia and congenital strabismus caused by complete or partial impairment of the 6th and 7th cranial nerves. <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> may be further associated with other nerves or malformations, mainly involving the extremities. The objective of this study was to quantify the decrease in oral motor performance in people with <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> compared with normoreactive individuals using the <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ral <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>otor <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ssessment <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale (<jats:styled-content style=\"fixed-case\">OMAS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study group comprised 33 subjects between the ages of 2 and 20\u00a0years (average age: 10\u00a0\u00b1\u00a05\u00a0years) with <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> along with 46 age\u2010 and gender\u2010matched control subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study group displayed a lower average functional score than the control group (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). A significant lack of lip closure (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.03) and anterior lingual seal during swallowing (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.03) occurred in the study group; in most cases, the individuals with <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> were classified as \u2018subfunctional\u2019. In addition, individuals with <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> in the older age group displayed better functional scores than those in the younger group (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Functional damage to oral motor function in individuals with <jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> is evident, but differs among patients with respect to severity and the movements that are compromised. However, overall, improvements in the functional patterns of these individuals can be observed as they mature in age.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jop.12107","type":"journal-article","created":{"date-parts":[[2013,8,10]],"date-time":"2013-08-10T06:34:46Z","timestamp":1376116486000},"page":"157-161","source":"Crossref","is-referenced-by-count":7,"title":["Oral motor assessment in individuals with <scp>M<\/scp>oebius syndrome"],"prefix":"10.1111","volume":"43","author":[{"given":"Adriana de Oliveira Lira","family":"Ortega","sequence":"first","affiliation":[{"name":"Department of Oral Pathology Special Care Dentistry Center School of Dentistry University of S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Joaquina","family":"Marques\u2010Dias","sequence":"additional","affiliation":[{"name":"Neurology Department Medicine School University of S\u00e3o Paulo S\u00e3o Paulo 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