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Aberrant productions of cytokines may lead to the onset of immune deficiency, allergy or autoimmunity, which are involved in the mechanisms of various immune\u2010mediated inflammatory diseases. Oral lichen planus (<jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>) is a chronic inflammation disease affecting the oral mucosa with unknown aetiology. Previous studies have described the abnormal expression patterns of various inflammation\u2010related cytokines, such as <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101, 2, 4, 5, 6, 8, 10, 12, 17, 18, <jats:styled-content style=\"fixed-case\">TGF<\/jats:styled-content>\u2010\u03b2, <jats:styled-content style=\"fixed-case\">IFN<\/jats:styled-content>\u2010\u03b3 and <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010\u03b1, in lesions, saliva, serum and peripheral blood mononuclear cells from patients with <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>, which may reflect the immune dysregulation status and emerge as central players in the immunopathogenesis of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>. Besides, the gene polymorphisms of several cytokines such as <jats:styled-content style=\"fixed-case\">IFN<\/jats:styled-content>\u2010\u03b3, <jats:styled-content style=\"fixed-case\">TNF<\/jats:styled-content>\u2010\u03b1, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20104, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201010 have been found to be involved in the susceptibility of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>. In this review, we gave a brief introduction of the characteristics and biological functions of these inflammation\u2010related cytokines and summarized for the first time the current knowledge on the involvement of inflammation\u2010related cytokines in <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>. Further research on the exact roles of these cytokines will aid the understanding of the pathogenesis and the identification of novel therapeutic approaches of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/jop.12142","type":"journal-article","created":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T11:50:11Z","timestamp":1387194611000},"page":"1-14","source":"Crossref","is-referenced-by-count":160,"title":["Inflammation\u2010related cytokines in oral lichen planus: an overview"],"prefix":"10.1111","volume":"44","author":[{"given":"Rui","family":"Lu","sequence":"first","affiliation":[{"name":"The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei\u2010MOST) and Key Laboratory of Oral Biomedicine Ministry of Education School and Hospital of Stomatology Wuhan University Wuhan PR China"},{"name":"Department of Oral Medicine School and Hospital of Stomatology Wuhan University Wuhan 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