{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T16:52:05Z","timestamp":1784739125386,"version":"3.55.0"},"reference-count":56,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,8,26]],"date-time":"2014-08-26T00:00:00Z","timestamp":1409011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content> may affect quality of life and impacts oral health and daily activities; consequently, psychological factors, dental needs and patients\u2019 perceptions. Professionals should understand this relation to adequately manage oral ulcers. This study aimed at investigating the relationship between oral health impacts, oral health\u2010related quality of life and psychological profiles in patients with recurrent aphthous stomatitis (<jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010three patients (30 men and 23 women, mean age: 31.1\u00a0\u00b1\u00a010.1\u00a0years) with <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content> participated in this study. During ulcer episodes, participants completed Hospital Anxiety and Depression Scale (<jats:styled-content style=\"fixed-case\">HAD<\/jats:styled-content>), Neuroticism\u2010Extraversion\u2010Openness Five Factor Inventory (<jats:styled-content style=\"fixed-case\">NEO<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content>), Oral Health Impact Profile (<jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content>\u201014) and United Kingdom Oral Health\u2010Related Quality of Life measure (<jats:styled-content style=\"fixed-case\">OHQ<\/jats:styled-content>oL\u2010<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>) proformas. Patients completed <jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content>\u201014 and <jats:styled-content style=\"fixed-case\">OHQ<\/jats:styled-content>oL\u2010<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> again when they were ulcer\u2010free. The statistically significance levels were set at <jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During ulcer episodes, patients reported worse oral health impacts and an inferior quality of life in comparison with ulcer\u2010free times (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). Higher <jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content> scores were significantly associated with higher <jats:styled-content style=\"fixed-case\">HAD<\/jats:styled-content> depression (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.036) and anxiety (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.012) scores. <jats:styled-content style=\"fixed-case\">NEO<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content> scores had no significant relations with <jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">OHQ<\/jats:styled-content>oL\u2010<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> scores (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). During ulcer\u2010free periods, no relationships were detected between <jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> OHQ<\/jats:styled-content>oL\u2010<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> HAD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">NEO<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">FFI<\/jats:styled-content> scores (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05), except between <jats:styled-content style=\"fixed-case\">OHQ<\/jats:styled-content>oL\u2010<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> and conscientiousness scores (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content> increased the negative oral health impacts on patients and consequently lowered their quality of life. Stressful situations and conditions (including anxiety and depression), rather than inherent personality profiles and stable psychological traits, were related to oral health impacts and quality of life in patients with <jats:styled-content style=\"fixed-case\">RAS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jop.12232","type":"journal-article","created":{"date-parts":[[2014,8,26]],"date-time":"2014-08-26T05:39:02Z","timestamp":1409031542000},"page":"278-283","source":"Crossref","is-referenced-by-count":73,"title":["Recurrent aphthous stomatitis (<scp>RAS<\/scp>): a preliminary within\u2010subject study of quality of life, oral health impacts and personality profiles"],"prefix":"10.1111","volume":"44","author":[{"given":"Mahmoud K.","family":"AL\u2010Omiri","sequence":"first","affiliation":[{"name":"Faculty of Dentistry University of Jordan Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jumana","family":"Karasneh","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Jordan University of Science and Technology Irbid Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohannad M.","family":"Alhijawi","sequence":"additional","affiliation":[{"name":"Department of Dentistry Ministry of Health Amman Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdalwhab M. 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