{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T01:32:12Z","timestamp":1719192732977},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T00:00:00Z","timestamp":1410480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Pediatric<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>is growing at an alarming rate in developing countries. Due to their compromised immune status, children infected with<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>are prone to a number of opportunistic infections. Oral manifestations are the first signs of the disease in many of them. To assess the oral mucosal status of Indian children with<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>, based on their<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4 cell counts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Two hundred and twenty one<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>infected children aged 6\u201318\u00a0years from various<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>centers, were divided into three groups, based on their<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4 cell counts; Group 1: \u2265500, Group 2: 201\u2013499 and Group 3: \u2264200\u00a0cells. The children in each group were further considered as \u2018prior to antiretroviral treatment (<jats:styled-content style=\"fixed-case\">ART<\/jats:styled-content>)\u2019 and \u2018on<jats:styled-content style=\"fixed-case\">ART<\/jats:styled-content>\u2019. Oral mucosal examination was done based on presumptive criteria given by Ramos\u2010Gomez for diagnosis of oro\u2010facial lesions commonly associated with<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>infection in children. Data obtained was subjected to statistical analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Angular cheilitis and pseudomembranous candidiasis were the frequently seen oral lesions. Children with<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>4 cell count \u2265500 had significantly fewer oral lesions each.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A high percentage of<jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected children were affected with oral mucosal lesions. There was a significant association between immune status and frequency of oral lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jop.12243","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T08:18:10Z","timestamp":1410509890000},"page":"296-299","source":"Crossref","is-referenced-by-count":8,"title":["Oral mucosal lesions and immune status in<scp>HIV<\/scp>\u2010infected Indian children"],"prefix":"10.1111","volume":"44","author":[{"given":"Priya","family":"Subramaniam","sequence":"first","affiliation":[{"name":"The Oxford Dental College and Hospital Pedodontics and Preventive Dentistry Bangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Kumar","sequence":"additional","affiliation":[{"name":"The Oxford Dental College and Hospital Pedodontics and Preventive Dentistry Bangalore 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