{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:21:14Z","timestamp":1788870074715,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T00:00:00Z","timestamp":1410480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Faculty of Dentistry Grant, Chulalongkorn University Fiscal year 2013"},{"name":"Research Unit in Oral Diseases"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2015,7]]},"abstract":"\n Objectives<\/jats:title>\n \n The aim of this study was to investigate the presence of serum antinuclear antibodies (\n ANA<\/jats:styled-content>\n ) in\n T<\/jats:styled-content>\n hai oral lichenoid drug reaction (\n OLDR<\/jats:styled-content>\n ) and oral lichen planus (\n OLP<\/jats:styled-content>\n ) patients.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and methods<\/jats:title>\n \n This study comprised 20 patients diagnosed with\n OLDR<\/jats:styled-content>\n , 23 patients with\n OLP<\/jats:styled-content>\n , and 24 healthy control subjects. Participants' blood samples were assayed for\n ANA<\/jats:styled-content>\n staining patterns and serum\n ANA<\/jats:styled-content>\n titer levels by immunofluorescence using human epithelial type 2 (\n HE<\/jats:styled-content>\n p\u20102) as a substrate. The serum\n ANA<\/jats:styled-content>\n titer levels were defined as low (1:40\u20131:80), medium (1:160\u20131:320), and high (>1:640).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Serum\n ANA<\/jats:styled-content>\n were detected in 73.9%, 70%, and 25% of\n OLP<\/jats:styled-content>\n ,\n OLDR<\/jats:styled-content>\n , and control subjects, respectively. There was a statistically significant difference between the number of serum\u2010\n ANA<\/jats:styled-content>\n \u2010positive subjects in the\n OLP<\/jats:styled-content>\n or\n OLDR<\/jats:styled-content>\n groups and the control group (\n P<\/jats:italic>\n \u00a0<\u00a00.01), but no significant difference between the\n OLP<\/jats:styled-content>\n and\n OLDR<\/jats:styled-content>\n groups. The speckled pattern was the most commonly found staining pattern, present in 60.9%, 55.0%, and 20.8% of the\n OLP<\/jats:styled-content>\n ,\n OLDR<\/jats:styled-content>\n , and control subjects, respectively. The number of subjects with low\n ANA<\/jats:styled-content>\n titers in the\n OLP<\/jats:styled-content>\n and\n OLDR<\/jats:styled-content>\n groups was significantly higher than that of the control group (\n P<\/jats:italic>\n \u00a0<\u00a00.01). Medium\n ANA<\/jats:styled-content>\n titers were found in 15%, 4.4%, and 4.2% of the\n OLDR<\/jats:styled-content>\n ,\n OLP<\/jats:styled-content>\n , and control subjects, respectively, while high\n ANA<\/jats:styled-content>\n titers were not found in any group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The number of serum\u2010\n ANA<\/jats:styled-content>\n \u2010positive\n OLP<\/jats:styled-content>\n and\n OLDR<\/jats:styled-content>\n patients was significantly higher than the control group. Speckled pattern and low titer levels were the most common findings in both\n OLP<\/jats:styled-content>\n and\n OLDR<\/jats:styled-content>\n groups\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jop.12257","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T04:20:00Z","timestamp":1410495600000},"page":"468-474","source":"Crossref","is-referenced-by-count":9,"title":["Oral lichenoid lesions and serum antinuclear antibodies in\n T<\/scp>\n hai patients"],"prefix":"10.1111","volume":"44","author":[{"given":"Chalakorn","family":"Prucktrakul","sequence":"first","affiliation":[{"name":"Oral Medicine Department, Faculty of Dentistry Chulalongkorn University Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pornpan","family":"Youngnak\u2010Piboonratanakit","sequence":"additional","affiliation":[{"name":"Oral Medicine Department, Faculty of Dentistry Chulalongkorn University Bangkok 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