{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:07:56Z","timestamp":1762866476156},"reference-count":52,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T00:00:00Z","timestamp":1410739200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Aim and objectives<\/jats:title><jats:p>To report on the prevalence of \u2018lichenoid dysplasia\u2019 (<jats:styled-content style=\"fixed-case\">LD<\/jats:styled-content>) in oral mucosal biopsies previously reported as oral lichen planus (<jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>), oral lichenoid lesion (<jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>) and oral epithelial dysplasia (<jats:styled-content style=\"fixed-case\">OED<\/jats:styled-content>). Based on this case series, to postulate whether features of dysplasia are present in biopsies with a diagnosis of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content> and vice versa that warrant a separate diagnostic entity of \u2018lichenoid dysplasia\u2019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>This retrospective, multicentre study was carried out by retrieving archival slides of cases diagnosed with <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> OLL<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">OED<\/jats:styled-content>. Diagnostic criteria for the study were based on published guidelines from seminal papers. A total of 165 cases, 70 <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content> and 95 epithelial dysplasia cases, were re\u2010examined. The diagnosis of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>s and <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>s was first reconfirmed according to published diagnostic criteria. They were then verified for microscopic features of epithelial dysplasia. Among cases of leukoplakia diagnosed with epithelial dysplasia, we further verified for the presence of lichenoid features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 70 cases of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content> were microscopically evaluated (<jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\u201054; <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>\u201016). Epithelial dysplasia was noted in 11 cases (<jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> \u2013 8 of 54; <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content> \u2013 3 of 16). Nineteen cases of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> (19 of 54) were found to bear features of <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>s as per published diagnostic criteria. Among the <jats:styled-content style=\"fixed-case\">OED<\/jats:styled-content> group, 22 of the 95 cases showed lichenoid features.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The study confirms lichenoid features may be found in <jats:styled-content style=\"fixed-case\">OED<\/jats:styled-content>s and epithelial dysplasia may be found in <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>. We reconfirm that these microscopic features may coexist. Our findings require further discussion by a panel of experts to redefine the entity known as \u2018lichenoid dysplasia\u2019. Future studies should address the concept of lichenoid dysplasia that may assist to resolve any controversies with regard to the malignant potential of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jop.12258","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T12:55:20Z","timestamp":1410785720000},"page":"507-514","source":"Crossref","is-referenced-by-count":24,"title":["Lichenoid dysplasia revisited \u2013 evidence from a review of Indian archives"],"prefix":"10.1111","volume":"44","author":[{"given":"Shankargouda","family":"Patil","sequence":"first","affiliation":[{"name":"Department of Oral Pathology and Microbiology Faculty of Dental Sciences M S Ramaiah University of Applied Sciences Bangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roopa S.","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology Faculty of Dental Sciences M S Ramaiah University of Applied Sciences Bangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. S.","family":"Sanketh","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology Faculty of Dental Sciences M S Ramaiah University of Applied Sciences Bangalore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saman","family":"Warnakulasuriya","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine King's College Dental Institute WHO Collaborating Centre for Oral Cancer London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1969.03150260091016"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(85)90315-9"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2007.00582.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/archderm.1985.01660090046011","article-title":"A histologic study of epithelial dysplasia in oral lichen planus","volume":"121","author":"Odukoya O","year":"1985","journal-title":"Arch Dermatol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(89)90115-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.06.076"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.2013.10"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2008.01441.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(03)00305-6"},{"key":"e_1_2_6_11_1","volume-title":"Pathology and genetics of head and neck tumours","author":"World Health Organization","year":"2005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2007.00584.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1001\/archderm.1973.01620260017005","article-title":"Cancer development in oral lichen planus. A follow\u2010up study of 327 patients","volume":"108","author":"Fulling HJ","year":"1973","journal-title":"Arch Dermatol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(85)90210-5"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1986.tb00580.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1992.tb01020.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0964-1955(97)00005-5"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1988.tb01528.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(98)80001-8"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(98)00116-X"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/ejso.1999.0689"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/ejso.2002.1302"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-200512000-00006"},{"key":"e_1_2_6_24_1","first-page":"261","article-title":"Oral lichen planus and malignant transformation: a retrospective follow\u2010up study of clinical and histopathologic data","volume":"37","author":"Bornstein MM","year":"2006","journal-title":"Quintessence Int"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2006.09.006"},{"key":"e_1_2_6_26_1","first-page":"235","article-title":"Malignant transformation of oral lichen planus: a retrospective study of 23 cases","volume":"40","author":"Fang M","year":"2009","journal-title":"Quintessence Int"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2011.01054.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(00)00096-8"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(99)70033-8"},{"key":"e_1_2_6_30_1","first-page":"194","article-title":"Malignant potential of oral lichen planus: a meta\u2010analysis","volume":"24","author":"Sousa FA","year":"2009","journal-title":"Rev Odontoci\u00eanc"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(98)90051-8"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(03)00161-6"},{"key":"e_1_2_6_33_1","first-page":"118","article-title":"Oral lichenoid disease as a premalignant condition: the controversies and the unknown","volume":"14","author":"Cort\u00e9s\u2010Ram\u00edrez DA","year":"2009","journal-title":"Med Oral Pathol Oral Cir Bucal"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1978.tb01879.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2003.00125.x"},{"key":"e_1_2_6_36_1","first-page":"310","article-title":"Oral lichen planus and oral lichenoid lesions; a critical appraisal with emphasis on the diagnostic aspects","volume":"14","author":"Waal I","year":"2009","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1808-8694(15)31102-2"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1999.tb02038.x"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1986.tb00621.x"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.02.020"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.18756"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2006.11.001"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2041-1626.2012.00130.x"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.57375"},{"key":"e_1_2_6_45_1","first-page":"ID 589569","article-title":"Oral contact lesions to mercury and dental amalgam\u2010 A review","author":"McParland H","year":"2012","journal-title":"J Biomed Biotech"},{"key":"e_1_2_6_46_1","first-page":"E224","article-title":"Letter to the editor: oral lichenoid disease. A new classification proposal","volume":"13","author":"Aguirre Urizar JM","year":"2008","journal-title":"Med Oral Pathol Oral Cir Bucal"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3780026"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-13-0001"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12169"},{"key":"e_1_2_6_50_1","first-page":"487","article-title":"Expression of Fas\/FasL in patients with oral lichen planus","volume":"14","author":"Hadzi\u2010Mihailovic M","year":"2009","journal-title":"J BUON"},{"key":"e_1_2_6_51_1","unstructured":"GainzaML CortesD UribarriA EchebarriaMA AguirreJM.Histological parameters of lesions clinically compatible with oral lichen planus. A study of 60 cases. Proceedings of Advances in Oral Cancer. IV th Symposium. University of del Pas Vasco. Bilbao Spain. 2012"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2005.11.022"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0722.2001.00081.x"}],"container-title":["Journal of Oral Pathology &amp; Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjop.12258","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjop.12258","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jop.12258","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T05:25:31Z","timestamp":1696224331000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jop.12258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,15]]},"references-count":52,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1111\/jop.12258"],"URL":"https:\/\/doi.org\/10.1111\/jop.12258","archive":["Portico"],"relation":{},"ISSN":["0904-2512","1600-0714"],"issn-type":[{"value":"0904-2512","type":"print"},{"value":"1600-0714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,15]]}}}