{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T13:24:23Z","timestamp":1769693063407,"version":"3.49.0"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,12,14]],"date-time":"2014-12-14T00:00:00Z","timestamp":1418515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009232","name":"University of Debrecen","doi-asserted-by":"crossref","award":["MEC-13\/2011"],"award-info":[{"award-number":["MEC-13\/2011"]}],"id":[{"id":"10.13039\/501100009232","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Oral human papillomavirus (<jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>) carriage rates were investigated in relation to genital <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> carriage in women with <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content>\u2010associated cervical lesions and male partner of such women, including several couples, in comparison with healthy individuals. Buccal and lingual mucosa of 60 males and 149 females with healthy oral mucosa and without known genital lesion, genital and oral mucosa of further 40 females with cervical high\u2010grade squamous intraepithelial lesion (<jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content>) and 34 male sexual partners of women with <jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content> (including 20 couples) were sampled. <jats:styled-content style=\"fixed-case\">HPV DNA<\/jats:styled-content> was detected using <jats:styled-content style=\"fixed-case\">MY<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">GP PCR<\/jats:styled-content>. Genotype was determined by sequencing or restriction fragment length polymorphism. Virus copy numbers were determined by real\u2010time <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>. Overall, oral <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> carriage rate was 5.7% (12\/209) in healthy individuals; average copy number was 5.8\u00a0\u00d7\u00a010<jats:sup>2<\/jats:sup>\u00a0copies\/1\u00a0\u03bcg <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>; male and female rates were comparable. Oral carriage in women with <jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content> was significantly higher, 20.0% (8\/40, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.003); males with partners with <jats:styled-content style=\"fixed-case\">HSIL<\/jats:styled-content> showed a carriage rate of 17.6% (6\/34), copy numbers were similar to the healthy controls. In contrast, genital carriage rate (52.9%, 18\/34 vs. 82.5%, 33\/40; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.006) and average copy number were lower in males (5.0\u00a0\u00d7\u00a010<jats:sup>5<\/jats:sup> vs. 7.8\u00a0\u00d7\u00a010<jats:sup>5<\/jats:sup>\u00a0copies\/1\u00a0\u03bcg <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content>;<jats:italic> P<\/jats:italic>\u00a0=\u00a00.01). Oral copy numbers in these groups and in healthy individuals were comparable. High\u2010risk genotypes were dominant; couples usually had the same genotype in the genital sample. In conclusion, genital <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> carriage is a risk factor of oral carriage for the individual or for the sexual partner, but alone is not sufficient to produce an oral <jats:styled-content style=\"fixed-case\">HPV<\/jats:styled-content> infection in most cases.<\/jats:p>","DOI":"10.1111\/jop.12302","type":"journal-article","created":{"date-parts":[[2014,12,15]],"date-time":"2014-12-15T04:56:46Z","timestamp":1418619406000},"page":"722-727","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence of human papillomaviruses in the healthy oral mucosa of women with high\u2010grade squamous intra\u2010epithelial lesion and of their partners as compared to healthy controls"],"prefix":"10.1111","volume":"44","author":[{"given":"T\u00edmea Zs\u00f3fia","family":"Tat\u00e1r","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology Faculty of Medicine University of Debrecen Debrecen 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