{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:32:16Z","timestamp":1761863536812},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,4,8]],"date-time":"2016-04-08T00:00:00Z","timestamp":1460073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","award":["CU\u201057\u2010075\u2010AS"],"award-info":[{"award-number":["CU\u201057\u2010075\u2010AS"]}],"id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study investigated the presence of serum antinuclear antibodies (<jats:styled-content style=\"fixed-case\">ANA<\/jats:styled-content>) profile and direct immunofluorescence (<jats:styled-content style=\"fixed-case\">DIF<\/jats:styled-content>) evaluation in elderly Thai patients with red and white oral lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Thirty\u2010two patients with red and white oral lesions were divided into two groups: group I consisted of 10 cases not taking medications, while group <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> consisted of 12 cases taking medications, and 30 healthy subjects as a control group. Blood samples were used to determine the <jats:styled-content style=\"fixed-case\">ANA<\/jats:styled-content> profile. <jats:styled-content style=\"fixed-case\">DIF<\/jats:styled-content> was investigated in the lesion containing groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Serum <jats:styled-content style=\"fixed-case\">ANA<\/jats:styled-content> was found in six cases (60%) in group I, eight cases (66.7%) in group <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>, and 19 cases (63.3%) in the control group. There were no significant differences between group I and group <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and the control group (<jats:italic>P<\/jats:italic> &gt; 0.05). Serum <jats:styled-content style=\"fixed-case\">ANA<\/jats:styled-content> was most commonly found in patients taking hypolipidemics (80%), followed by antihypertensives (71.4%), <jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>s (50%), hypoglycemics (50%), and others (66.7%). The anticytoplasmic staining frequency in group <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> was higher compared with group I and the control group. Anti\u2010ds<jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> antibodies were not found in any group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Elderly patients with red and white oral lesions who were taking medications had a higher serum <jats:styled-content style=\"fixed-case\">ANA<\/jats:styled-content> frequency than group I and the control group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jop.12444","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T18:26:38Z","timestamp":1460312798000},"page":"797-802","source":"Crossref","is-referenced-by-count":5,"title":["Correlation of serum <scp>ANA<\/scp> and direct immunofluorescence studies in elderly Thai patients with red and white oral lesions"],"prefix":"10.1111","volume":"45","author":[{"given":"Kobkan","family":"Thongprasom","sequence":"first","affiliation":[{"name":"Oral Medicine Department Faculty of Dentistry Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chanwit","family":"Prapinjumrune","sequence":"additional","affiliation":[{"name":"Oral Medicine Department Faculty of Dentistry Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patnarin","family":"Kanjanabuch","sequence":"additional","affiliation":[{"name":"Oral Medicine Department Faculty of Dentistry Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pornpan","family":"Youngnak\u2010Piboonratanakit","sequence":"additional","affiliation":[{"name":"Oral Medicine Department Faculty of Dentistry Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Titipong","family":"Preuksrisakul","sequence":"additional","affiliation":[{"name":"Oral Medicine Department Faculty of Dentistry Chulalongkorn University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12458"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/014556130408300316"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12257"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"S25\u2010e1","DOI":"10.1016\/j.tripleo.2006.11.001","article-title":"Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations","volume":"103","author":"Al\u2010Hashimi I","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"e_1_2_7_6_1","first-page":"2","article-title":"Oral lichen planus: a retrospective comparative study between Thai and Croatian patients","volume":"17","author":"Thongprasom K","year":"2009","journal-title":"Acta Dermatovenerol Croat"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2041-1626.2010.00005.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.57375"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01142.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2004.01024.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2014.09.009"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10561"},{"key":"e_1_2_7_13_1","first-page":"E287","article-title":"Sensitivity of direct immunofluorescence in oral diseases. 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