{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:57:13Z","timestamp":1789585033790,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,18]],"date-time":"2016-07-18T00:00:00Z","timestamp":1468800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Oral lichen planus (\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      ) and oral lichenoid lesions (\n                      <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>\n                      ) are considered potentially malignant disorders with a cancer incidence of around 1% of cases, although this estimation is controversial. The aim of this study was to analyze the cancer incidence in a case series of patients with\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>\n                      and to explore clinicopathological aspects that may cause underestimation of the cancer incidence in these diseases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective study was conducted of 102 patients diagnosed with\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      (\n                      <jats:italic>n<\/jats:italic>\n                      = 21, 20.58%) or\n                      <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>\n                      (\n                      <jats:italic>n<\/jats:italic>\n                      = 81) between January 2006 and January 2016. Patients were informed of the risk of malignization and followed up annually. The number of sessions programmed for each patient was compared with the number actually attended. Follow\u2010up was classified as complete (100% attendance), good (75\u201399%), moderate (25\u201374%), or poor (&lt;25% attendance) compliance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Cancer was developed by four patients (3.9%), three males and one male. One of these developed three carcinomas, which were diagnosed at the follow\u2010up visit (two in lower gingiva, one in floor of mouth); one had\n                      <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>\n                      and the other three had\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      . The carcinoma developed in mucosal areas with no\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      or\n                      <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>\n                      involvement in three of these patients, while\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      and cancer were diagnosed simultaneously in the fourth. Of the six carcinomas diagnosed, five (83.3%) were T1 and one (16.7%) T2. None were N+, and all patients remain alive and disease\u2010free.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The cancer incidence in\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">OLL<\/jats:styled-content>\n                      appears to be underestimated due to the strict exclusion criteria usually imposed.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.12480","type":"journal-article","created":{"date-parts":[[2016,7,18]],"date-time":"2016-07-18T07:36:58Z","timestamp":1468827418000},"page":"148-153","source":"Crossref","is-referenced-by-count":31,"title":["Is oral cancer incidence among patients with oral lichen planus\/oral lichenoid lesions underestimated?"],"prefix":"10.1111","volume":"46","author":[{"given":"M. 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