{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:10:23Z","timestamp":1787314223569,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,12,11]],"date-time":"2016-12-11T00:00:00Z","timestamp":1481414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007801","name":"Fundaci\u00f3n S\u00e9neca","doi-asserted-by":"publisher","award":["19894\/GERM\/15"],"award-info":[{"award-number":["19894\/GERM\/15"]}],"id":[{"id":"10.13039\/100007801","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      The aim of this study was to evaluate oxidative stress factors and C\u2010reactive protein in the saliva of patients with oral lichen planus (\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      ) and burning mouth syndrome (\n                      <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This consecutive, cross\u2010sectional study included 20 patients with\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      , 19 with burning mouth syndrome (\n                      <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>\n                      ), and 31 control subjects. The oral cavity of each patient was examined and patients responded to a quality of life questionnaire (\n                      <jats:styled-content style=\"fixed-case\">OHIP<\/jats:styled-content>\n                      \u201014) and the xerostomia inventory. The following parameters were measured in whole non\u2010stimulated saliva: trolox equivalent antioxidant capacity (\n                      <jats:styled-content style=\"fixed-case\">TEAC<\/jats:styled-content>\n                      ); total antioxidant capacity (\n                      <jats:styled-content style=\"fixed-case\">TAC<\/jats:styled-content>\n                      ); cupric reducing antioxidant capacity (\n                      <jats:styled-content style=\"fixed-case\">CUPRAC<\/jats:styled-content>\n                      ); ferric reducing ability of plasma (\n                      <jats:styled-content style=\"fixed-case\">FRAP<\/jats:styled-content>\n                      ); C\u2010reactive protein (\n                      <jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>\n                      ); nitric oxide; nitrates; and nitrites.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      group presented statistically significant differences in reactive oxygen species (\n                      <jats:styled-content style=\"fixed-case\">ROS<\/jats:styled-content>\n                      ) (29 600 cps) in comparison with the control group (39 679 cps) (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). In the\n                      <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>\n                      group,\n                      <jats:styled-content style=\"fixed-case\">ROS<\/jats:styled-content>\n                      was 29 707 cps with significant difference in comparison with the control group (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05). Significantly higher salivary nitric oxide (145.7 \u03bcmol) and nitrite (141.0 \u03bcmol) levels were found in\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      patients in comparison with control group (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Increases in nitric oxide and C\u2010reactive protein were found in the saliva of\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      patients in comparison with\n                      <jats:styled-content style=\"fixed-case\">BMS<\/jats:styled-content>\n                      and control patients. Further studies are required to confirm these findings.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.12522","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T09:50:39Z","timestamp":1478598639000},"page":"387-392","source":"Crossref","is-referenced-by-count":70,"title":["Evaluation of salivary oxidate stress biomarkers, nitric oxide and C\u2010reactive protein in patients with oral lichen planus and burning mouth syndrome"],"prefix":"10.1111","volume":"46","author":[{"given":"Asta","family":"Tvarijonaviciute","sequence":"first","affiliation":[{"name":"Interdisciplinary Laboratory of Clinical Analysis Interlab\u2010UMU Faculty of Veterinary Medicine Regional Campus of International Excellence Campus Mare Nostrum University of Murcia Espinardo Murcia Spain"},{"name":"Department of Animal Medicine and Surgery Veterinary School the Autonomous University of Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Aznar\u2010Cayuela","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Faculty of Medicine University of Murcia Espinardo Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila P.","family":"Rubio","sequence":"additional","affiliation":[{"name":"Interdisciplinary Laboratory of Clinical Analysis Interlab\u2010UMU Faculty of Veterinary Medicine Regional Campus of International Excellence Campus Mare Nostrum University of Murcia Espinardo Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 J.","family":"Ceron","sequence":"additional","affiliation":[{"name":"Interdisciplinary Laboratory of Clinical Analysis Interlab\u2010UMU Faculty of Veterinary Medicine Regional Campus of International Excellence Campus Mare Nostrum University of Murcia Espinardo Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia","family":"L\u00f3pez\u2010Jornet","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Faculty of Medicine University of Murcia Espinardo Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,11]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2015.04.005"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2015.00073"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/154411130301400405"},{"key":"e_1_2_5_5_1","first-page":"E310","article-title":"Oral lichen planus and oral lichenoid lesions; 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