{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:36:11Z","timestamp":1787495771533,"version":"build-2736575974"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T00:00:00Z","timestamp":1507852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2018,1]]},"abstract":"\n Background<\/jats:title>\n \n Oral potentially malignant disorders (\n OPMD<\/jats:styled-content>\n s) could have a significant psychological impact on patients, principally because of the unknown risk of malignant transformation, while the physical and functional impairments could differ. This study aimed to assess the impact of three different\n OPMD<\/jats:styled-content>\n s and their disease stages on the quality of life (QoL) of affected patients.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Oral leukoplakia (\n OL<\/jats:styled-content>\n ), oral lichen planus (\n OLP<\/jats:styled-content>\n ) and oral submucous fibrosis (\n OSF<\/jats:styled-content>\n ) patients who were undergoing treatment at an oral medicine clinic of a dental teaching hospital in India were the study population. All subjects completed the recently developed\n OPMDQ<\/jats:styled-content>\n oL questionnaire and a short form 12 item (version 2) health survey questionnaire (\n SF<\/jats:styled-content>\n \u201012v2).\n OPMDQ<\/jats:styled-content>\n oL questionnaire consists of 20 items over four dimensions. A higher score denotes poor\n OHRQ<\/jats:styled-content>\n oL.\n SF<\/jats:styled-content>\n \u201012v2 has two components, a Physical Component Summary (\n PCS<\/jats:styled-content>\n ) and Mental Component Summary (\n MCS<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 150 subjects (50 each of\n OL<\/jats:styled-content>\n ,\n OLP<\/jats:styled-content>\n and\n OSF<\/jats:styled-content>\n ) participated.\n OL<\/jats:styled-content>\n patients (37.7\u00a0\u00b1\u00a07.9) reported significantly better\n OPMDQ<\/jats:styled-content>\n oL scores than\n OLP<\/jats:styled-content>\n (47.3\u00a0\u00b1\u00a05.8) and\n OSF<\/jats:styled-content>\n (45.4\u00a0\u00b1\u00a09.2) patients.\n OLP<\/jats:styled-content>\n patients reported significant problems in obtaining a clear diagnosis for their condition, more so than the other\n OPMD<\/jats:styled-content>\n s.\n OL<\/jats:styled-content>\n patients reported fewer problems for the dimension, \u201cphysical impairment and functional limitations\u201d than the\n OLP<\/jats:styled-content>\n and\n OSF<\/jats:styled-content>\n patients. A significant trend was observed with the overall\n OPMDQ<\/jats:styled-content>\n oL and\n MCS<\/jats:styled-content>\n , deteriorating as the disease stage increased.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n OLP<\/jats:styled-content>\n and\n OSF<\/jats:styled-content>\n have a significant impact on the QoL of affected individuals:\n OL<\/jats:styled-content>\n less so. Increasing stage of the disease is associated with worsening QoL.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jop.12620","type":"journal-article","created":{"date-parts":[[2017,8,2]],"date-time":"2017-08-02T06:19:09Z","timestamp":1501654749000},"page":"60-65","source":"Crossref","is-referenced-by-count":46,"title":["Impact of oral potentially malignant disorders on quality of life"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2518-6476","authenticated-orcid":false,"given":"Jyothi","family":"Tadakamadla","sequence":"first","affiliation":[{"name":"Menzies Health Institute Queensland and School of Dentistry and Oral Health Griffith University Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santhosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Menzies Health Institute Queensland and School of Dentistry and Oral Health Griffith University Qld 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