{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:18:49Z","timestamp":1792156729681,"version":"4.4.0"},"reference-count":49,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T00:00:00Z","timestamp":1542672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>\n                    Fibrous dysplasia is a non\u2010neoplastic developmental process that affects the craniofacial bones, characterized by painless enlargement as a result of bone substitution by abnormal fibrous tissue. Postzygotic somatic activating mutations in the\n                    <jats:italic>GNAS1<\/jats:italic>\n                    gene cause fibrous dysplasia and have been extensively investigated, as well as being helpful in the differential diagnosis of the disease. Fibrous dysplasia may involve one (monostotic) or multiple bones (polyostotic), sporadically or in association with McCune\u2010Albright syndrome, Jeffe\u2010Lichenstein syndrome, or Mazabreud syndrome. This review summarizes the current knowledge on fibrous dysplasia, emphasizing the value of integrating the understanding of its molecular pathogenesis with the clinical, radiological, and histopathological features. In addition, we address important aspects related to the differential diagnosis and patient management.\n                  <\/jats:p>","DOI":"10.1111\/jop.12797","type":"journal-article","created":{"date-parts":[[2018,10,30]],"date-time":"2018-10-30T12:10:28Z","timestamp":1540901428000},"page":"3-9","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Fibrous dysplasia of the jaws: Integrating molecular pathogenesis with clinical, radiological, and histopathological features"],"prefix":"10.1111","volume":"48","author":[{"given":"Tha\u00eds dos Santos Fontes","family":"Pereira","sequence":"first","affiliation":[{"name":"Department of Oral Surgery and Pathology School of Dentistry Universidade Federal de Minas Gerais (UFMG) Belo Horizonte Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Cavalieri","family":"Gomes","sequence":"additional","affiliation":[{"name":"Department of 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