{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:29:17Z","timestamp":1792798157344,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"S\u00e3o Paulo State Research Foundation","award":["2017\/14880-3"],"award-info":[{"award-number":["2017\/14880-3"]}],"id":[{"id":"https:\/\/ror.org\/02ddkpn78","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Diffuse large B\u2010cell lymphoma, NOS (DLBCL NOS) is the commonest extranodal non\u2010Hodgkin lymphoma diagnosed in the oral and maxillofacial region. However, few studies are currently available and its prognostic determinants remain undefined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To analyse the available data on oral DLBCL NOS and to describe its clinicopathological features, identifying potential prognostic factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An electronic systematic search was performed using multiple databases with a specific search strategy in April 2018. All reports describing DLBCL NOS involving the oral cavity and jaw bones with sufficient clinicopathological information were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixty\u2010three publications were included in the study, comprising 122 cases. Oral DLBCL NOS was found predominantly in elderly males (61.5%), and most often presented as an asymptomatic swelling of the gingiva. Patients commonly were HIV\u2010negative (36.1%), with few reports describing EBV\u2010positive cases (four cases\/3.3%). Only eight cases presented B symptoms and most cases were classified as stage I or II (48.4%). CHOP therapy was the main treatment option (24.5%) and the overall 5\u2010year survival rate achieved 83%. Males and advanced Ann Arbor stage patients presented significantly lower survival rates in the univariate analysis, but no significance was found in the multivariate model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Oral DLBCL NOS is an aggressive malignancy, but with a high survival rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.12802","type":"journal-article","created":{"date-parts":[[2018,11,10]],"date-time":"2018-11-10T06:19:50Z","timestamp":1541830790000},"page":"185-191","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Clinicopathological analysis of oral diffuse large B\u2010cell lymphoma, NOS: A systematic review"],"prefix":"10.1111","volume":"48","author":[{"given":"Carla Isabelly","family":"Rodrigues\u2010Fernandes","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Lacerda","family":"de Souza","sequence":"additional","affiliation":[{"name":"Service of Oral Pathology Jo\u00e3o de Barros Barreto University Hospital Federal University of Par\u00e1 Bel\u00e9m Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara Ferreira dos","family":"Santos\u2010Costa","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery and Pathology School of Dentistry Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lder Ant\u00f4nio Rebelo","family":"Pontes","sequence":"additional","affiliation":[{"name":"Service of Oral Pathology Jo\u00e3o de Barros Barreto University Hospital Federal University of Par\u00e1 Bel\u00e9m Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oslei 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Maxillofacial Surgery Queen Alexandra Hospital Portsmouth UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Paiva","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"},{"name":"Department of Oral Surgery and Pathology School of Dentistry Universidade Federal de Minas Gerais Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2012.01.018"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474086.2018.1506326"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2013.197"},{"key":"e_1_2_6_5_1","first-page":"291","volume-title":"World Health Organization classification of Tumours of Hematopoietic and Lymphoid Tissues","author":"Gascoyne 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