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It is likely that what initiates the OLP disease process is a complex interaction of host susceptibility and environmental triggers. While it is possible that OLP represents a true autoimmune condition against an epithelial autoantigen, the mechanisms that lead to this immune dysregulation are still poorly understood. In this review article, we discuss current concepts relating to the immunopathogenesis of OLP, as well as the potential contributory roles the oral microbiota and mucosal\u2010associated invariant T (MAIT) cells.<\/jats:p>","DOI":"10.1111\/jop.12898","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T07:29:57Z","timestamp":1559892597000},"page":"552-559","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["The immunopathogenesis of oral lichen planus\u2014Is there a role for mucosal associated invariant T cells?"],"prefix":"10.1111","volume":"48","author":[{"given":"Lara M.","family":"DeAngelis","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Dentistry and Health Sciences, Melbourne Dental School The University of Melbourne Carlton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Cirillo","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Dentistry and Health Sciences, Melbourne Dental School The University of Melbourne Carlton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"McCullough","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Dentistry and Health Sciences, Melbourne Dental School The University of Melbourne Carlton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.51875"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1987.tb00480.x"},{"key":"e_1_2_7_4_1","first-page":"1","article-title":"A prevalence study of oral mucosal lesions in an adult Swedish population","volume":"36","author":"Axell T","year":"1976","journal-title":"Odontol Revy Suppl"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2010.00946.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2002.tb00540.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0738-081X(00)00142-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12415"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/154411130201300405"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0904-2512.2001.10063.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03355.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-0960.1993.tb00860.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1978.tb01879.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.1997.tb00015.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.2001.70408.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2011.12.008"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016350601137251"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2002.00097.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(85)90262-2"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1985.tb00528.x"},{"issue":"3","key":"e_1_2_7_21_1","first-page":"981","article-title":"Pillars Article: control of regulatory T cell development by the transcription factor Foxp3. 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