{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:31:02Z","timestamp":1790361062076,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T00:00:00Z","timestamp":1594252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The presence and grading of oral epithelial dysplasia (OED) are considered the gold standard for predicting the malignant risk of oral potentially malignant disorders. However, inter\u2010observer and intra\u2010observer agreement in the context of reporting on OED grading has been reputedly considered unreliable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We undertook a multi\u2010centre study of six Indian oral pathologists to assess variations in reporting OED using the World Health Organization (WHO; 2005) system and also the recently introduced binary system. The observer variability was assessed with the use of kappa statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The weighted kappa intra\u2010observer agreement scores improved (\u03ba\n                      <jats:sub>w<\/jats:sub>\n                      \u00a0=\u00a00.5012) on grouping by two grades as no and mild dysplasia versus moderate and severe dysplasia compared to binary grading system (\u03ba\u00a0=\u00a00.1563) and WHO grading system (\u03ba\n                      <jats:sub>w<\/jats:sub>\n                      \u00a0=\u00a00.4297). Poor to fair inter\u2010observer agreement scores were seen between the principal investigator (PI) and the other five observers using the WHO grading system (\u03ba\u00a0=\u00a00.051\u20100.231; \u03ba\n                      <jats:sub>w<\/jats:sub>\n                      \u00a0=\u00a00.145 to 0.361; 35% to 46%) and binary grading system (\u03ba\u00a0=\u00a00.049 to 0.326; 50 to 65%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is considerable room for improvement in the assessment of OED using either system to help in standardised reporting. The professional pathology organisations in India should take steps to provide external quality assessment in reporting OED among oral and general pathologists who are engaged in routine reporting of head and neck specimens.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jop.13056","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T17:18:38Z","timestamp":1591723118000},"page":"948-955","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Intra\u2010observer and inter\u2010observer variability in two grading systems for oral epithelial dysplasia: A multi\u2010centre study in India"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2149-4145","authenticated-orcid":false,"given":"Kannan","family":"Ranganathan","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Ragas Dental College and Hospital Chennai India"},{"name":"The Tamil Nadu Dr. MGR Medical University Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7647-0234","authenticated-orcid":false,"given":"Loganathan","family":"Kavitha","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Ragas Dental College and Hospital Chennai India"},{"name":"The Tamil Nadu Dr. MGR Medical University Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Sharada","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillo Facial Pathology AECS Maaruti College of Dental Sciences Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radhika M.","family":"Bavle","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Krishnadevaraya College of Dental Sciences Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roopa S.","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology Faculty of Dental Sciences Ramaiah University of Applied Sciences Bangaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita M.","family":"Pattanshetty","sequence":"additional","affiliation":[{"name":"Maratha Mandal's NGH Institute of Dental Sciences &amp; Research Centre Belagavi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay K.","family":"Hazarey","sequence":"additional","affiliation":[{"name":"Datta Meghe Institute of Medical Sciences Wardha India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6261-2681","authenticated-orcid":false,"given":"Murittige Gopalakrishna","family":"Madhura","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology DAPM R V Dental College and Hospital Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tejavathi","family":"Nagaraj","sequence":"additional","affiliation":[{"name":"Sri Rajiv Gandhi College of Dental sciences &amp; Hospital Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Lingappa","sequence":"additional","affiliation":[{"name":"Bapuji Dental College &amp; Hospital Davangere India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2103-0746","authenticated-orcid":false,"given":"Saman","family":"Warnakulasuriya","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry Oral &amp; Craniofacial Sciences King's College London WHO Collaborating Centre for Oral Cancer London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(78)90383-3"},{"key":"e_1_2_9_3_1","first-page":"177","volume-title":"World Health Organization classification of Tumours: Pathology and genetics of Tumours of the Head and neck","author":"Gale N","year":"2005"},{"key":"e_1_2_9_4_1","first-page":"112","volume-title":"WHO Classification of Tumours of the Head and Neck. 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