{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T10:46:57Z","timestamp":1758970017318,"version":"3.40.5"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,6,28]],"date-time":"2020-06-28T00:00:00Z","timestamp":1593302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Oral Pathology Medicine"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Burning mouth syndrome (BMS) is a chronic pain disorder affecting the oral cavity. Previous work has shown promising analgesic results of bodily illusions in other chronic pain conditions. The aim of this proof\u2010of\u2010concept, pilot study was to investigate whether bodily illusions reduce pain in BMS patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nine participants diagnosed with BMS underwent bodily illusions using a MIRAGE\u2010mediated reality system. All participants completed four conditions and performed standardised movements of the tongue. First, a baseline condition was performed while the tongue was viewed at normal size and colour. Then, three conditions were performed in random order: resizing shrink, colour\u2010based (blue tongue) and incongruent movement illusions. During each condition, participants rated overall pain intensity and the intensity of burning pain\/sensation on the tongue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no difference in overall pain intensity ratings between conditions. However, a significant effect of condition was found for burning pain\/sensation of the tongue. The colour illusion significantly reduced burning pain compared with baseline (MD\u00a0=\u00a0\u221212.8, 95% CI \u221220.7 to \u22124.8), corresponding to an average pain reduction of 32%. Exploratory analyses showed the colour illusion also significantly reduced pain compared with the shrink illusion (MD\u00a0=\u00a0\u221211.7, 95% CI \u221222.2 to \u22121.1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Using visual illusions to change tongue colour to blue resulted in significant reductions in burning pain\/sensations in BMS patients for the duration of the illusion. This proof\u2010of\u2010concept study suggests that BMS patients may benefit from bodily illusions, and supports additional research using larger samples and more comprehensive control conditions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jop.13065","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T22:04:32Z","timestamp":1591999472000},"page":"505-513","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The effect of multisensory illusions on pain and perceived burning sensations in patients with Burning Mouth Syndrome: A proof\u2010of\u2010concept study"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6226-0682","authenticated-orcid":false,"given":"Amanda H.","family":"Phoon Nguyen","sequence":"first","affiliation":[{"name":"UWA Dental School The University of Western Australia Perth WA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh","family":"Balasubramaniam","sequence":"additional","affiliation":[{"name":"UWA Dental School The University of Western Australia Perth WA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Bellan","sequence":"additional","affiliation":[{"name":"Cognitive and Systems Neuroscience Research Hub (CSN\u2010RH) University of South Australia Adelaide SA Australia"},{"name":"Innovation, Implementation and Clinical Translation (IIMPACT) University of South Australia Adelaide SA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger N.","family":"Newport","sequence":"additional","affiliation":[{"name":"School of Sport, Exercise and Health Sciences Loughborough University Loughborough UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tasha R.","family":"Stanton","sequence":"additional","affiliation":[{"name":"Innovation, Implementation and Clinical Translation (IIMPACT) University of South Australia Adelaide SA Australia"},{"name":"Neuroscience Research Australia Randwick NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,28]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"IASP(2016).IASP orofacial pain fact sheet. 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